Pharmacological potential of tocotrienols: a review

H Ahsan, A Ahad, J Iqbal, WA Siddiqui - Nutrition & metabolism, 2014 - Springer
Tocotrienols, members of the vitamin E family, are natural compounds found in a number of
vegetable oils, wheat germ, barley, and certain types of nuts and grains. Like tocopherols …

Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases

BB Aggarwal, C Sundaram, S Prasad… - Biochemical …, 2010 - Elsevier
Initially discovered in 1938 as a “fertility factor,” vitamin E now refers to eight different
isoforms that belong to two categories, four saturated analogues (α, β, γ, and δ) called …

[HTML][HTML] A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein

PP Cavicchia, SE Steck, TG Hurley, JR Hussey… - The Journal of …, 2009 - Elsevier
Inflammation is associated with a number of chronic conditions, such as cancer and
cardiovascular disease. Reducing inflammation may help prevent or treat these conditions …

[HTML][HTML] The implication of reactive oxygen species and antioxidants in knee osteoarthritis

NB Tudorachi, EE Totu, A Fifere, V Ardeleanu… - Antioxidants, 2021 - mdpi.com
Knee osteoarthritis (KOA) is a chronic multifactorial pathology and a current and essential
challenge for public health, with a negative impact on the geriatric patient's quality of life …

Cancer-preventive activities of tocopherols and tocotrienols

J Ju, SC Picinich, Z Yang, Y Zhao, N Suh… - …, 2010 - academic.oup.com
The cancer-preventive activity of vitamin E has been studied. Whereas some
epidemiological studies have suggested a protective effect of vitamin E against cancer …

The role of vitamin E in preventing and treating osteoarthritis–a review of the current evidence

KY Chin, S Ima-Nirwana - Frontiers in pharmacology, 2018 - frontiersin.org
Osteoarthritis is a debilitating disease of the joint involving cartilage degeneration and
chondrocytes apoptosis. Oxidative stress is one of the many proposed mechanisms …

Tocotrienol research: past into present

RSY Wong, AK Radhakrishnan - Nutrition reviews, 2012 - academic.oup.com
The vitamin E family consists of eight isomers known as alpha-, beta-, gamma-, and delta-
tocopherols and alpha-, beta-, gamma-, and delta-tocotrienols. Numerous studies focused …

Tocotrienols: the emerging face of natural vitamin E

CK Sen, S Khanna, C Rink, S Roy - Vitamins & Hormones, 2007 - Elsevier
Natural vitamin E includes eight chemically distinct molecules: α‐, β‐, γ‐, and δ‐tocopherols
and α‐, β‐, γ‐, and δ‐tocotrienols. More than 95% of all studies on vitamin E are directed …

Tocotrienols fight cancer by targeting multiple cell signaling pathways

R Kannappan, SC Gupta, JH Kim, BB Aggarwal - Genes & nutrition, 2012 - Springer
Cancer cells are distinguished by several distinct characteristics, such as self-sufficiency in
growth signal, resistance to growth inhibition, limitless replicative potential, evasion of …

The molecular mechanism of vitamin E as a bone-protecting agent: a review on current evidence

SK Wong, NV Mohamad, NI Ibrahim, KY Chin… - International journal of …, 2019 - mdpi.com
Bone remodelling is a tightly-coordinated and lifelong process of replacing old damaged
bone with newly-synthesized healthy bone. In the bone remodelling cycle, bone resorption …