The TNF family of ligands and receptors: communication modules in the immune system and beyond

C Dostert, M Grusdat, E Letellier… - Physiological …, 2019‏ - journals.physiology.org
The tumor necrosis factor (TNF) and TNF receptor (TNFR) superfamilies (TNFSF/TNFRSF)
include 19 ligands and 29 receptors that play important roles in the modulation of cellular …

Overview of the immune response

DD Chaplin - Journal of allergy and clinical immunology, 2010‏ - Elsevier
The immune system has evolved to protect the host from a universe of pathogenic microbes
that are themselves constantly evolving. The immune system also helps the host eliminate …

Facilitating T cell infiltration in tumor microenvironment overcomes resistance to PD-L1 blockade

H Tang, Y Wang, LK Chlewicki, Y Zhang, J Guo… - Cancer cell, 2016‏ - cell.com
Immune checkpoint blockade therapies fail to induce responses in the majority of cancer
patients, so how to increase the objective response rate becomes an urgent challenge …

[HTML][HTML] The TNF and TNF receptor superfamilies: integrating mammalian biology

RM Locksley, N Killeen, MJ Lenardo - Cell, 2001‏ - cell.com
The TNF and TNF Receptor Superfamilies: Cell Skip to Main Content Skip to Main Menu
Advertisement Cell This journal offers authors two options (open access or subscription) to …

The two NF-κB activation pathways and their role in innate and adaptive immunity

G Bonizzi, M Karin - Trends in immunology, 2004‏ - cell.com
NF-κB was first described as a B-cell-specific transcription factor that binds the κB site in the
Ig κ light chain enhancer. Soon after, NF-κB activity was found to be inducible in all cell types …

Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

D Tracey, L Klareskog, EH Sasso, JG Salfeld… - Pharmacology & …, 2008‏ - Elsevier
During the past 30 years, elucidation of the pathogenesis of rheumatoid arthritis, Crohn's
disease, psoriasis, psoriatic arthritis and ankylosing spondylitis at the cellular and molecular …

[کتاب][B] Wintrobe's clinical hematology

MM Wintrobe - 2008‏ - books.google.com
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host

M Barthel, S Hapfelmeier… - Infection and …, 2003‏ - journals.asm.org
Salmonella enterica subspecies 1 serovar Typhimurium is a principal cause of human
enterocolitis. For unknown reasons, in mice serovar Typhimurium does not provoke …

A chemokine-driven positive feedback loop organizes lymphoid follicles

KM Ansel, VN Ngo, PL Hyman, SA Luther, R Förster… - Nature, 2000‏ - nature.com
Lymphoid follicles are B-cell-rich compartments of lymphoid organs that function as sites of
B-cell antigen encounter and differentiation. CXC chemokine receptor-5 (CXCR5) is …

The who, how and where of antigen presentation to B cells

FD Batista, NE Harwood - Nature Reviews Immunology, 2009‏ - nature.com
A functional immune system depends on the appropriate activation of lymphocytes following
antigen encounter. In this Review, we summarize studies that have used high-resolution …