Viral epidemics develop from the emergence of new variants of infectious viruses. The lack
of effective antiviral treatments for the new viral infections coupled with rapid community …

Anaerobic ammonium oxidation (anammox) represents a promising technology for
wastewater nitrogen removal. Organics management is critical to achieving efficient and …

There is a need to better understand and handle the'dark matter'of proteomics—the vast
diversity of post-translational and chemical modifications that are unaccounted in a typical …

Fixing cells with paraformaldehyde (PFA) is an essential step in numerous biological
techniques as it is thought to preserve a snapshot of biomolecular transactions in living cells …

Anaerobic ammonium oxidation (Anammox), a process ideally suited for the treatment of
nitrogen-rich wastewater streams, is a promising novel biological nitrogen elimination …

Formaldehyde has been used for decades to probe macromolecular structure and function
and to trap complexes, cells, and tissues for further analysis. Formaldehyde crosslinking is …

Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

Once focused mainly on the characterization of neoplasms, immunohistochemistry (IHC)
today is used in the investigation of a broad range of disease processes with applications in …

Rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) is a method
that allows the study of protein complexes, in particular chromatin and transcription factor …

Mammalian bodies have more than a billion cells per cubic centimeter, which makes whole-
body cell (WBC) profiling of an organism one of the ultimate challenges in biology and …