Decoding Toll-like receptors: Recent insights and perspectives in innate immunity

T Kawai, M Ikegawa, D Ori, S Akira - Immunity, 2024 - cell.com
Toll-like receptors (TLRs) are an evolutionarily conserved family in the innate immune
system and are the first line of host defense against microbial pathogens by recognizing …

Candida albicans and Candida glabrata: global priority pathogens

M Katsipoulaki, MHT Stappers… - Microbiology and …, 2024 - journals.asm.org
SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination

S Fourati, LE Tomalin, MP Mulè, DG Chawla… - Nature …, 2022 - nature.com
Several studies have shown that the pre-vaccination immune state is associated with the
antibody response to vaccination. However, the generalizability and mechanisms that …

Progress in chitin analytics

MV Tsurkan, A Voronkina, Y Khrunyk… - Carbohydrate …, 2021 - Elsevier
Chitin is the second most abundant biopolymer and functions as the main structural
component in a variety of living organisms. In nature, chitin rarely occurs in a pure form, but …

Can SARS-CoV-2 virus use multiple receptors to enter host cells?

LK Gadanec, KR McSweeney, T Qaradakhi… - International journal of …, 2021 - mdpi.com
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …

Rewilding of laboratory mice enhances granulopoiesis and immunity through intestinal fungal colonization

YH Chen, F Yeung, KA Lacey, K Zaldana, JD Lin… - Science …, 2023 - science.org
The paucity of blood granulocyte populations such as neutrophils in laboratory mice is a
notable difference between this model organism and humans, but the cause of this species …

Discriminating symbiosis and immunity signals by receptor competition in rice

C Zhang, J He, H Dai, G Wang, X Zhang… - Proceedings of the …, 2021 - pnas.org
Plants encounter various microbes in nature and must respond appropriately to symbiotic or
pathogenic ones. In rice, the receptor-like kinase OsCERK1 is involved in recognizing both …

Biotechnologically produced chitosans with nonrandom acetylation patterns differ from conventional chitosans in properties and activities

S Sreekumar, J Wattjes, A Niehues, T Mengoni… - Nature …, 2022 - nature.com
Chitosans are versatile biopolymers with multiple biological activities and potential
applications. They are linear copolymers of glucosamine and N-acetylglucosamine defined …

Hide-and-seek: chitin-triggered plant immunity and fungal counterstrategies

BQ Gong, FZ Wang, JF Li - Trends in plant science, 2020 - cell.com
Fungal pathogens are major destructive microorganisms for land plants and pose growing
challenges to global crop production. Chitin is a vital building block for fungal cell walls and …

[HTML][HTML] Battle royale: innate recognition of poxviruses and viral immune evasion

H Yu, RC Bruneau, G Brennan, S Rothenburg - Biomedicines, 2021 - mdpi.com
Host pattern recognition receptors (PRRs) sense pathogen-associated molecular patterns
(PAMPs), which are molecular signatures shared by different pathogens. Recognition of …