Targeting cancer stem cell pathways for cancer therapy

L Yang, P Shi, G Zhao, J Xu, W Peng, J Zhang… - Signal transduction and …, 2020 - nature.com
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

CD36 tango in cancer: signaling pathways and functions

J Wang, Y Li - Theranostics, 2019 - pmc.ncbi.nlm.nih.gov
CD36, a scavenger receptor expressed in multiple cell types, mediates lipid uptake,
immunological recognition, inflammation, molecular adhesion, and apoptosis. CD36 is a …

Drug resistance and Cancer stem cells

Y Li, Z Wang, JA Ajani, S Song - Cell Communication and Signaling, 2021 - Springer
Therapy resistance is a major problem when treating cancer patients as cancer cells
develop mechanisms that counteract the effect of therapeutic compounds, leading to fit and …

A unique understanding of traditional medicine of pomegranate, Punica granatum L. and its current research status

S Ge, L Duo, J Wang, J Yang, Z Li, Y Tu - Journal of ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Pomegranate, Punica granatum L., has been
used in traditional medicine in China and several regions of the world including Ayurveda …

PPAR-α modulators as current and potential cancer treatments

Y Tan, M Wang, K Yang, T Chi, Z Liao, P Wei - Frontiers in oncology, 2021 - frontiersin.org
Cancer is one of the leading causes of mortality worldwide. PPAR modulators may hold
great potential for the management of cancer patients. Indeed, PPARs are critical sensors …

Cannabidiol goes nuclear: The role of PPARγ

S Khosropoor, MS Alavi, L Etemad, A Roohbakhsh - Phytomedicine, 2023 - Elsevier
Background Cannabidiol (CBD) is one of the main phytocannabinoids found in Cannabis
sativa. In contrast to Δ9-tetrahydrocannabinol, it has a low affinity for cannabinoid receptors …

[HTML][HTML] Lipid metabolism and cancer

H Cheng, M Wang, J Su, Y Li, J Long, J Chu, X Wan… - Life, 2022 - mdpi.com
Lipid metabolism is involved in the regulation of numerous cellular processes, such as cell
growth, proliferation, differentiation, survival, apoptosis, inflammation, movement, membrane …

Diverse roles of fatty acid binding proteins (FABPs) in development and pathogenesis of cancers

M Amiri, S Yousefnia, FS Forootan, M Peymani… - Gene, 2018 - Elsevier
One of the most importantly involved pathways in cancer development is fatty-acid signaling
pathway. Synthesized lipids as energetic sources are consumed by cancer cells for …

Competitive glucose metabolism as a target to boost bladder cancer immunotherapy

J Afonso, LL Santos, A Longatto-Filho… - Nature Reviews …, 2020 - nature.com
Bladder cancer—the tenth most frequent cancer worldwide—has a heterogeneous natural
history and clinical behaviour. The predominant histological subtype, urothelial bladder …

Evodiamine: a review of its pharmacology, toxicity, pharmacokinetics and preparation researches

Q Sun, L **e, J Song, X Li - Journal of Ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Evodia rutaecarpa, a well-known herb medicine in China,
is extensively applied in traditional Chinese medicine (TCM). The plant has the effects of …