AI in drug discovery and its clinical relevance

R Qureshi, M Irfan, TM Gondal, S Khan, J Wu, MU Hadi… - Heliyon, 2023 - cell.com
The COVID-19 pandemic has emphasized the need for novel drug discovery process.
However, the journey from conceptualizing a drug to its eventual implementation in clinical …

Challenges of unculturable bacteria: environmental perspectives

A Bodor, N Bounedjoum, GE Vincze… - … Science and Bio …, 2020 - Springer
Environmental biotechnology offers several promising techniques for the rehabilitation of
polluted environments. The modern industrialized world presents novel challenges to the …

Insights into nitrogen and phosphorus metabolic mechanisms of algal-bacterial aerobic granular sludge via metagenomics: Performance, microbial community and …

W **ong, S Wang, Y **, Z Wu, D Liu, H Su - Bioresource Technology, 2023 - Elsevier
Aiming to propose the potential mechanism for the enhancement of nitrogen (N) and
phosphorus (P) removal of algal-bacterial aerobic granular sludge (A-AGS), metagenomic …

Eubiosis and dysbiosis: the two sides of the microbiota

V Iebba, V Totino, A Gagliardi, F Santangelo… - New …, 2016 - iris.uniroma1.it
The microbial ecosystem of the gastrointestinal tract is characterized by a great number of
microbial species living in balance by adopting mutualistic strategies. The …

Denitrification performance and microbial versatility in response to different selection pressures

R Pishgar, JA Dominic, Z Sheng, JH Tay - Bioresource technology, 2019 - Elsevier
This study investigated functional dynamics of microbial community in response to different
selection pressures, with a focus on denitrification. Suspended-biomass experiments …

Deep learning for drug-induced liver injury

Y Xu, Z Dai, F Chen, S Gao, J Pei… - Journal of chemical …, 2015 - ACS Publications
Drug-induced liver injury (DILI) has been the single most frequent cause of safety-related
drug marketing withdrawals for the past 50 years. Recently, deep learning (DL) has been …

Standard methods for Apis mellifera propolis research

V Bankova, D Bertelli, R Borba, BJ Conti… - Journal of Apicultural …, 2019 - Taylor & Francis
Propolis is one of the most fascinating honey bee (Apis mellifera L.) products. It is a plant
derived product that bees produce from resins that they collect from different plant organs …

Microbial management of anaerobic digestion: exploiting the microbiome-functionality nexus

M Carballa, L Regueiro, JM Lema - Current opinion in biotechnology, 2015 - Elsevier
Highlights•Requirements for microbial management in anaerobic digestion are
revised.•Bacterial evenness and active Archaea population are proposed as microbial …

[PDF][PDF] The Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)

T Van de Wiele, P Van den Abbeele… - The Impact of Food …, 2015 - library.oapen.org
This chapter provides a general explanation of the Simulator of the Human Intestinal
Microbial Ecosystem (SHIME®). The SHIME is one of the few gut models that mimics the …

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the …

AW Walker, JD Sanderson, C Churcher, GC Parkes… - BMC microbiology, 2011 - Springer
Background The gut microbiota is thought to play a key role in the development of the
inflammatory bowel diseases Crohn's disease (CD) and ulcerative colitis (UC). Shifts in the …