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Piperidine derivatives: recent advances in synthesis and pharmacological applications
NA Frolov, AN Vereshchagin - International Journal of Molecular Sciences, 2023 - mdpi.com
Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …
a significant role in the pharmaceutical industry. Their derivatives are present in more than …
Bioactive natural compounds and antioxidant activity of essential oils from spice plants: New findings and potential applications
L Diniz do Nascimento, AA Barbosa de Moraes… - Biomolecules, 2020 - mdpi.com
Spice plants have a great influence on world history. For centuries, different civilizations
have used them to condiment the foods of kings and nobles and applied them as embalming …
have used them to condiment the foods of kings and nobles and applied them as embalming …
Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …
[HTML][HTML] Protective effects of medicinal plant-based foods against diabetes: a review on pharmacology, phytochemistry, and molecular mechanisms
Diabetes mellitus (DM) comprises a range of metabolic disorders characterized by high
blood glucose levels caused by defects in insulin release, insulin action, or both. DM is a …
blood glucose levels caused by defects in insulin release, insulin action, or both. DM is a …
Experimental investigations on active solar dryers integrated with thermal storage for drying of black pepper
This study focusses on the experimental analyses of two active horizontal solar dryers viz.,
mixed mode (Case-I) and indirect solar dryer (Case-II) integrated with latent heat storage …
mixed mode (Case-I) and indirect solar dryer (Case-II) integrated with latent heat storage …
Binding mechanism and antioxidant activity of piperine to hemoglobin
X Hu, D Wu, L Tang, J Zhang, Z Zeng, F Geng, H Li - Food Chemistry, 2022 - Elsevier
Piperine (PIP) is the most active main component in pepper. The interaction of small
molecules with biomolecules leads to structural and functional changes. In this study, the …
molecules with biomolecules leads to structural and functional changes. In this study, the …
Driving forces and large scale affinity calculations for piperine/γ-cyclodxetrin complexes: Mechanistic insights from umbrella sampling simulation and DFT calculations
Piperine (PiP), a bioactive molecule, exhibits numerous health benefits and is frequently
employed as a co-delivery agent with various phytomedicines (eg, curcumin) to enhance …
employed as a co-delivery agent with various phytomedicines (eg, curcumin) to enhance …
Green synthesis of Piper nigrum copper-based nanoparticles: in silico study and ADMET analysis to assess their antioxidant, antibacterial, and cytotoxic effects
M Kiranmayee, N Rajesh, M Vidya Vani… - Frontiers in …, 2023 - frontiersin.org
Nanobiotechnology is a popular branch of science that is gaining interest among scientists
and researchers as it allows for the green manufacturing of nanoparticles by employing …
and researchers as it allows for the green manufacturing of nanoparticles by employing …
Thymoquinone, piperine, and sorafenib combinations attenuate liver and breast cancers progression: epigenetic and molecular docking approaches
Background Traditional herbal medicine has been used for centuries to cure many
pathological disorders, including cancer. Thymoquinone (TQ) and piperine (PIP) are major …
pathological disorders, including cancer. Thymoquinone (TQ) and piperine (PIP) are major …
Gut metabolites predict Clostridioides difficile recurrence
JJ Dawkins, JR Allegretti, TE Gibson, E McClure… - Microbiome, 2022 - Springer
Background Clostridioides difficile infection (CDI) is the most common hospital acquired
infection in the USA, with recurrence rates> 15%. Although primary CDI has been …
infection in the USA, with recurrence rates> 15%. Although primary CDI has been …