Skeletal muscle possesses a remarkable regenerative capacity that relies on the activity of
muscle stem cells, also known as satellite cells. The presence of non-myogenic cells also …

Striated muscle is a highly plastic and regenerative organ that regulates body movement,
temperature, and metabolism—all the functions needed for an individual's health and well …

The characterization of fibro/adipogenic progenitor cells (FAPs) in the skeletal muscle has
contributed to modify the monocentric view of muscle regeneration beyond muscle satellite …

Abstract Fibro/Adipogenic Progenitors (FAPs) are muscle-interstitial progenitors mediating
pro-myogenic signals that are critical for muscle homeostasis and regeneration. In …

Excessive accumulation of intermuscular adipose tissue (IMAT) is a common pathological
feature in various metabolic and health conditions and can cause muscle atrophy, reduced …

In Duchenne muscular dystrophy (DMD), the absence of the dystrophin protein causes a
variety of poorly understood secondary effects. Notably, muscle fibers of dystrophic …

Muscular fatty infiltration is a common and troublesome pathology after rotator cuff tears
(RCT), which mainly derives from fibro-adipogenic progenitors (FAPs). Compared to the …

Autoreactive B cells are assumed to play a critical role in pemphigus; however, the
characteristics of these cells are not yet fully understood. In this study, 23 pemphigus …

Following injury, skeletal muscle regenerates but fatty tissue accumulation is seen in aged
muscle or muscular dystrophies. Fibro/adipogenic progenitors (FAPs) are key players in …

Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by
releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non …