Multiple sclerosis: emerging epidemiological trends and redefining the clinical course

E Portaccio, M Magyari, EK Havrdova… - The Lancet Regional …, 2024 - thelancet.com
Multiple sclerosis is a chronic, inflammatory, and neurodegenerative disease of the central
nervous system and a major cause of neurological disability in young adults. Its prevalence …

Microbiome in multiple sclerosis: where are we, what we know and do not know

MK Boziki, E Kesidou, P Theotokis, AFA Mentis… - Brain sciences, 2020 - mdpi.com
An increase of multiple sclerosis (MS) incidence has been reported during the last decade,
and this may be connected to environmental factors. This review article aims to encapsulate …

Leveraging real-world data to investigate multiple sclerosis disease behavior, prognosis, and treatment

JA Cohen, M Trojano, EM Mowry… - Multiple sclerosis …, 2020 - journals.sagepub.com
Randomized controlled clinical trials and real-world observational studies provide
complementary information but with different validity. Some clinical questions (disease …

[HTML][HTML] Psychometric properties of the Pittsburgh Sleep Quality Index (PSQI) in patients with multiple sclerosis: factor structure, reliability, correlates, and …

A Jerković, U Mikac, M Matijaca, V Košta… - Journal of clinical …, 2022 - mdpi.com
Sleep disturbances and poor sleep are a common complaint in the population with multiple
sclerosis (MS) disease. The most commonly reported scale is the Pittsburgh Sleep Quality …

Age-related adverse events of disease-modifying treatments for multiple sclerosis: a meta-regression

L Prosperini, S Haggiag, C Tortorella… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Objective: To verify the hypothesis of an age-dependent increase of infections and
neoplasms in patients with multiple sclerosis (MS) under disease-modifying treatments …

[HTML][HTML] Therapeutic effects of catechins in less common neurological and neurodegenerative disorders

G Sebastiani, L Almeida-Toledano, M Serra-Delgado… - Nutrients, 2021 - mdpi.com
In recent years, neurological and neurodegenerative disorders research has focused on
altered molecular mechanisms in search of potential pharmacological targets, eg …

E-health and multiple sclerosis

PM Matthews, VJ Block, L Leocani - Current opinion in neurology, 2020 - journals.lww.com
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Initial treatment strategy and clinical outcomes in Finnish MS patients: a propensity-matched study

K Hänninen, M Viitala, S Atula, SM Laakso… - Journal of …, 2022 - Springer
Background The optimal treatment strategy with disease-modifying therapies (DMTs) in
relapsing–remitting multiple sclerosis (RRMS) remains uncertain. Objective To compare …

B cell depletion in the treatment of multiple sclerosis

KM Myhr, Ø Torkildsen, A Lossius, L Bø… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous
system. The latest development of B-cell depletion by anti-CD20 monoclonal antibodies has …

Multiple sclerosis in Finland 2018—Data from the national register

SM Laakso, M Viitala, H Kuusisto… - Acta Neurologica …, 2019 - Wiley Online Library
Objectives Finland is a high‐risk multiple sclerosis (MS) region, but a national MS register
has not existed until 2014. In this paper, we present the Finnish MS register variables and …