Harnessing DNA computing and nanopore decoding for practical applications: from informatics to microRNA-targeting diagnostics

S Takiguchi, N Takeuchi, V Shenshin… - Chemical Society …, 2024 - pubs.rsc.org
DNA computing represents a subfield of molecular computing with the potential to become a
significant area of next-generation computation due to the high programmability inherent in …

Cell-free systems: A synthetic biology tool for rapid prototy** in metabolic engineering

K Jeung, M Kim, E Jang, YJ Shon, GY Jung - Biotechnology Advances, 2025 - Elsevier
Microbial cell factories provide sustainable alternatives to petroleum-based chemical
production using cost-effective substrates. A deep understanding of their metabolism is …

Functional analysis of single enzymes combining programmable molecular circuits with droplet-based microfluidics

G Gines, R Espada, A Dramé-Maigné… - Nature …, 2024 - nature.com
The analysis of proteins at the single-molecule level reveals heterogeneous behaviours that
are masked in ensemble-averaged techniques. The digital quantification of enzymes …

DNA circuit-based immunoassay for ultrasensitive protein pattern classification

A Masurier, R Sieskind, G Gines, Y Rondelez - Analyst, 2024 - pubs.rsc.org
Cytokines are important immune modulators, and pivotal biomarkers for the diagnostic of
various diseases. In standard analytical procedure, each protein is detected individually …

Robust Sequence Design Space for the Isothermal Exponential Amplification of Short Oligonucleotides

YS Ang, LYL Yung - Small, 2024 - Wiley Online Library
Advances in isothermal amplification techniques have accelerated development in
biosensing applications and the design of complex molecular devices. The exponential …