Fluorescent probe strategy for live cell distinction
Live cell discrimination is the first and essential step to understand complex biosystems.
Conventional cell discrimination involving various antibodies relies on selective surface …
Conventional cell discrimination involving various antibodies relies on selective surface …
Self‐assembled peptide‐based nanomaterials for biomedical imaging and therapy
GB Qi, YJ Gao, L Wang, H Wang - Advanced materials, 2018 - Wiley Online Library
Peptide‐based materials are one of the most important biomaterials, with diverse structures
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …
Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction
The ability to detect low numbers of microbial cells in food and clinical samples is highly
valuable but remains a challenge. Here we present a detection system (called 'APC-Cas') …
valuable but remains a challenge. Here we present a detection system (called 'APC-Cas') …
Interrogating amyloid aggregates using fluorescent probes
Amyloids are a broad class of proteins and peptides that can misfold and assemble into long
unbranched fibrils with a cross-β conformation. These misfolding and aggregation events …
unbranched fibrils with a cross-β conformation. These misfolding and aggregation events …
[HTML][HTML] The role of functional amyloids in bacterial virulence
Amyloid fibrils are best known as a product of human and animal protein misfolding
disorders, where amyloid formation is associated with cytotoxicity and disease. It is now …
disorders, where amyloid formation is associated with cytotoxicity and disease. It is now …
Multiplexed identification of bacterial biofilm infections based on machine-learning-aided lanthanide encoding
J Wang, Z Jiang, Y Wei, W Wang, F Wang, Y Yang… - ACS …, 2022 - ACS Publications
Pathogenic biofilms are up to 1000-fold more drug-resistant than planktonic pathogens and
cause about 80% of all chronic infections worldwide. The lack of prompt and reliable biofilm …
cause about 80% of all chronic infections worldwide. The lack of prompt and reliable biofilm …
Confocal microscopy imaging of the biofilm matrix
The extracellular matrix is an integral part of microbial biofilms and an important field of
research. Confocal laser scanning microscopy is a valuable tool for the study of biofilms, and …
research. Confocal laser scanning microscopy is a valuable tool for the study of biofilms, and …
A conformationally restricted aza-BODIPY platform for stimulus-responsive probes with enhanced photoacoustic properties
Photoacoustic (PA) dyes, which absorb near-infrared (NIR) light to generate an ultrasonic
signal, can be detected at centimeter depths in tissues with significantly higher resolution …
signal, can be detected at centimeter depths in tissues with significantly higher resolution …
Activated alkyne-enabled turn-on click bioconjugation with cascade signal amplification for ultrafast and high-throughput antibiotic screening
S Lv, C Wang, K Xue, J Wang, M **ao… - Proceedings of the …, 2023 - National Acad Sciences
Antimicrobial susceptibility testing plays a pivotal role in the discovery of new antibiotics.
However, the development of simple, sensitive, and rapid assessment approaches remains …
However, the development of simple, sensitive, and rapid assessment approaches remains …
Multiplexed instrument-free bar-chart spinchip integrated with nanoparticle-mediated magnetic aptasensors for visual quantitative detection of multiple pathogens
A portable multiplexed bar-chart SpinChip (MB-SpinChip) integrated with nanoparticle-
mediated magnetic aptasensors was developed for visual quantitative instrument-free …
mediated magnetic aptasensors was developed for visual quantitative instrument-free …