Human neuroimaging has demonstrated the existence of large-scale functional networks in
the cerebral cortex consisting of topographically distant brain regions with functionally …

Basolateral amygdala (BLA) projects widely across the macaque frontal cortex, and
amygdalo-frontal projections are critical for appropriate emotional responding and decision …

Importance Mania/hypomania is the pathognomonic feature of bipolar disorder (BD).
Established, reliable neural markers denoting mania/hypomania risk to help with early risk …

Cognitive flexibility is an executive functioning skill that develops in childhood, and when
impaired, has transdiagnostic implications for psychiatric disorders. To identify how intrinsic …

Background The zona incerta (ZI) is involved in mediating survival behaviors and is
connected to a wide range of cortical and subcortical structures, including key basal ganglia …

Ventrolateral prefrontal cortex (vlPFC), dorsolateral prefrontal cortex (dlPFC), and temporal
cortex (TE) all contribute to visual decision-making. Accumulating evidence suggests that …

Individual preferences for the flavor of different foods and fluids exert a strong influence on
behavior. Most current theories posit that preferences are integrated with other state …

Rationale An imbalance of the tryptophan kynurenine pathway (KP) commonly occurs in
psychiatric disorders, though the neurocognitive and network-level effects of this aberration …

The “hard problem” of explaining phenomenal consciousness and its relationship to brain-
based physical processes has long occupied thinkers in fields ranging from neuroscience to …

Background: The frontal lobe is affected by Alzheimer's disease (AD) and mild cognitive
impairment (MCI). However, we still lack sufficient understanding of subregion atrophy in the …