Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Decades of research have disclosed a plethora of alterations in protein glycosylation that
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …

Introduction: MUC16 is overexpressed in multiple cancers and plays an important role in
tumorigenicity and acquired resistance to therapy. Area covered: In this review, we describe …

Simple Summary The detection of colorectal cancer (CRC) at an early stage is increasing
due to the implementation of screening programs. Local excision of early CRC is potentially …

Cancer remains a leading cause of death worldwide due to the lack of safer and more
effective therapies. Cancer vaccines developed from neoantigens are an emerging strategy …

Protein glycosylation is ubiquitous in biological systems and plays essential roles in many
cellular events. Global and site‐specific analysis of glycoproteins in complex biological …

Advanced-stage solid primary tumors and metastases often express mucin 16 (MUC16),
carrying immature glycans such as the Tn antigen, resulting in specific glycoproteoforms not …

Glycosylation is one of the most significant post-translational modifications occurring to
proteins, since it affects some of their basic properties, such as their half-life or biological …

Glycosylation is the most commonly occurring post-translational modifications, and is
believed to modify over 50% of all proteins. The process of glycan modification is directed by …

Rationale: Bladder cancer (BC) management demands the introduction of novel molecular
targets for precision medicine. Cell surface glycoprotein CD44 has been widely studied as a …