Microfluidic technologies for cell deformability cytometry

H Chen, J Guo, F Bian, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Microfluidic detection methods for cell deformability cytometry have been regarded as
powerful tools for single‐cell analysis of cellular mechanical phenotypes, thus having been …

Micro total analysis systems. Latest advancements and trends

PS Dittrich, K Tachikawa, A Manz - Analytical chemistry, 2006 - ACS Publications
The area of micro total analysis systems (μTAS), also called “lab on a chip”, miniaturized or
microfluidic analysis systems, is a rapidly develo** field. During the last several years, we …

Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system

FN Lolo, N Walani, E Seemann, D Zalvidea… - Nature cell …, 2023 - nature.com
In response to different types and intensities of mechanical force, cells modulate their
physical properties and adapt their plasma membrane (PM). Caveolae are PM nano …

AFM indentation study of breast cancer cells

QS Li, GYH Lee, CN Ong, CT Lim - Biochemical and biophysical research …, 2008 - Elsevier
Mechanical properties of individual living cells are known to be closely related to the health
and function of the human body. Here, atomic force microscopy (AFM) indentation using a …

Extracting cell stiffness from real-time deformability cytometry: theory and experiment

A Mietke, O Otto, S Girardo, P Rosendahl… - Biophysical journal, 2015 - cell.com
Cell stiffness is a sensitive indicator of physiological and pathological changes in cells, with
many potential applications in biology and medicine. A new method, real-time deformability …

Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation

AAS Bhagat, HW Hou, LD Li, CT Lim, J Han - Lab on a Chip, 2011 - pubs.rsc.org
Blood is a highly complex bio-fluid with cellular components making up> 40% of the total
volume, thus making its analysis challenging and time-consuming. In this work, we introduce …

Microfluidic approaches for cancer cell detection, characterization, and separation

J Chen, J Li, Y Sun - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the recent developments in microfluidic technologies for in vitro cancer
diagnosis. We summarize the working principles and experimental results of key microfluidic …

Biomechanics approaches to studying human diseases

GYH Lee, CT Lim - Trends in biotechnology, 2007 - cell.com
Nanobiomechanics has recently been identified as an emerging field that can potentially
make significant contributions in the study of human diseases. Research into biomechanics …

Recent advances in microfluidic techniques for single-cell biophysical characterization

Y Zheng, J Nguyen, Y Wei, Y Sun - Lab on a Chip, 2013 - pubs.rsc.org
Biophysical (mechanical and electrical) properties of living cells have been proven to play
important roles in the regulation of various biological activities at the molecular and cellular …

Microfluidics technology for manipulation and analysis of biological cells

C Yi, CW Li, S Ji, M Yang - Analytica chimica acta, 2006 - Elsevier
Analysis of the profiles and dynamics of molecular components and sub-cellular structures
in living cells using microfluidic devices has become a major branch of bioanalytical …