Multiscale cancer modeling

TS Deisboeck, Z Wang, P Macklin… - Annual review of …, 2011 - annualreviews.org
Simulating cancer behavior across multiple biological scales in space and time, ie,
multiscale cancer modeling, is increasingly being recognized as a powerful tool to refine …

Mathematical modeling of tumor growth and treatment

H Enderling, M AJ Chaplain - Current pharmaceutical design, 2014 - benthamdirect.com
Using mathematical models to simulate dynamic biological processes has a long history.
Over the past couple of decades or so, quantitative approaches have also made their way …

Nonlinear modelling of cancer: bridging the gap between cells and tumours

JS Lowengrub, HB Frieboes, F **, YL Chuang, X Li… - …, 2009 - iopscience.iop.org
Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

[書籍][B] Multiscale modeling of cancer: an integrated experimental and mathematical modeling approach

V Cristini, J Lowengrub - 2010 - books.google.com
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining
tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial …

[書籍][B] Elliptic partial differential equations

V Volpert - 2014 - Springer
If we had to formulate in one sentence what this book is about, it might be “How partial
differential equations can help to understand heat explosion, tumor growth or evolution of …

[書籍][B] Dynamics of cancer: mathematical foundations of oncology

D Wodarz, N Komarova - 2014 - books.google.com
The book aims to provide an introduction to mathematical models that describe the
dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for …

A chemotaxis-haptotaxis model: the roles of nonlinear diffusion and logistic source

Y Tao, M Winkler - SIAM Journal on Mathematical Analysis, 2011 - SIAM
This paper deals with a chemotaxis-haptotaxis model of cancer invasion of tissue
(extracellular matrix (ECM)). The model consists of a parabolic chemotaxis-haptotaxis PDE …

Three-dimensional multispecies nonlinear tumor growth—II: tumor invasion and angiogenesis

HB Frieboes, F **, YL Chuang, SM Wise… - Journal of theoretical …, 2010 - Elsevier
We extend the diffuse interface model developed in Wise et al.(2008) to study nonlinear
tumor growth in 3-D. Extensions include the tracking of multiple viable cell species …

Second order convex splitting schemes for periodic nonlocal Cahn–Hilliard and Allen–Cahn equations

Z Guan, JS Lowengrub, C Wang, SM Wise - Journal of Computational …, 2014 - Elsevier
We devise second-order accurate, unconditionally uniquely solvable and unconditionally
energy stable schemes for the nonlocal Cahn–Hilliard (nCH) and nonlocal Allen–Cahn …

A mathematical framework for modelling the metastatic spread of cancer

LC Franssen, T Lorenzi, AEF Burgess… - Bulletin of mathematical …, 2019 - Springer
Cancer is a complex disease that starts with mutations of key genes in one cell or a small
group of cells at a primary site in the body. If these cancer cells continue to grow successfully …