The crucial role of prolactin-lactogenic hormone in Covid-19

HM Al-Kuraishy, AI Al-Gareeb, M Butnariu… - Molecular and Cellular …, 2022 - Springer
Prolactin (PRL) is a peptide hormone secreted from anterior pituitary involved in milk
production in the females and regulation of sex drive in both sexes. PRL has pro …

The effects of prolactin on the immune system, its relationship with the severity of COVID-19, and its potential immunomodulatory therapeutic effect

Y Rasmi, L Jalali, S Khalid, A Shokati, P Tyagi, A Ozturk… - Cytokine, 2023 - Elsevier
Prolactin (PRL) is an endocrine hormone secreted by the anterior pituitary gland that has a
variety of physiological effects, including milk production, immune system regulation, and …

Baicalin ameliorates lipopolysaccharide-induced acute lung injury in mice by suppressing oxidative stress and inflammation via the activation of the Nrf2-mediated HO …

X Meng, L Hu, W Li - Naunyn-Schmiedeberg's Archives of Pharmacology, 2019 - Springer
This research aims to investigate the ameliorative potential of baicalin on lipopolysaccharide-
induced acute lung injury by the suppression of oxidative stress and inflammation via the …

Polygonatum sibiricum polysaccharides prevent LPS-induced acute lung injury by inhibiting inflammation via the TLR4/Myd88/NF-κB pathway

TY Liu, LL Zhao, SB Chen, BC Hou… - Experimental and …, 2020 - spandidos-publications.com
Inflammation plays an important role in cases of acute lung injury (ALI), and the Toll-like
receptor 4/nuclear factor-κB (TLR4/NF-κB) pathway, which can be regulated by …

The role of ROS-pyroptosis in PM2. 5 induced air-blood barrier destruction

M Wei, Y Cong, J Lei, R Du, M Yang, X Lu… - Chemico-Biological …, 2023 - Elsevier
Abstract Fine particulate matter (PM 2.5) has attracted increasing attention due to its health-
threatening effects. Although numerous studies have investigated the impact of PM 2.5 on …

Curcumin reduces LPS-induced septic acute kidney injury through suppression of lncRNA PVT1 in mice

W Huang, X Li, D Wang, Y Sun, Q Wang, Y Bu, F Niu - Life sciences, 2020 - Elsevier
Objective To investigate the protective effects of curcumin on LPS-induced septic acute
kidney injury and to explore its underlying molecular mechanisms. Methods A mouse model …

Potential pharmaceuticals targeting neuroimmune interactions in treating acute lung injury

D Wu, X Liao, J Gao, Y Gao, Q Li… - Clinical and …, 2024 - Wiley Online Library
Background and main body Although interactions between the nervous and immune
systems have been recognized decades ago, it has become increasingly appreciated that …

NLRC5 negatively regulates inflammatory responses in LPS-induced acute lung injury through NF-κB and p38 MAPK signal pathways

Y Wang, C Huang, E Bian, T Lei, X Lv, J Li - Toxicology and Applied …, 2020 - Elsevier
Acute lung injury is an acute inflammatory disease with high morbidity rate and high
mortality rate. However, there is still no effective clinical treatment to date. Our previous …

Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

Z Fu, X Wu, F Zheng, Y Zhang - BMC pulmonary medicine, 2022 - Springer
Background Sevoflurane is considered as a lung-protective factor in acute lung injury (ALI),
but the underlying molecular mechanism remains largely unknown. The present study …

Sevoflurane alleviates LPS‑induced acute lung injury via the microRNA‑27a‑3p/TLR4/MyD88/NF‑κB signaling pathway

Y Wang, X Zhang, J Tian, G Liu… - … journal of molecular …, 2019 - spandidos-publications.com
Acute lung injury (ALI) is a critical syndrome that is associated with a high morbidity and
mortality in patients. Sevoflurane has a lung protective effect in ALI as it reportedly has anti …