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Structural identifiability analysis of epidemic models based on differential equations: a tutorial-based primer
The successful application of epidemic models hinges on our ability to estimate model
parameters from limited observations reliably. An often-overlooked step before estimating …
parameters from limited observations reliably. An often-overlooked step before estimating …
A novel methodology for epidemic risk assessment of COVID-19 outbreak
We propose a novel data-driven framework for assessing the a-priori epidemic risk of a
geographical area and for identifying high-risk areas within a country. Our risk index is …
geographical area and for identifying high-risk areas within a country. Our risk index is …
Reconstructing higher-order interactions in coupled dynamical systems
Higher-order interactions play a key role for the operation and function of a complex system.
However, how to identify them is still an open problem. Here, we propose a method to fully …
However, how to identify them is still an open problem. Here, we propose a method to fully …
How robust are estimates of key parameters in standard viral dynamic models?
Mathematical models of viral infection have been developed, fitted to data, and provide
insight into disease pathogenesis for multiple agents that cause chronic infection, including …
insight into disease pathogenesis for multiple agents that cause chronic infection, including …
An integrated framework for building trustworthy data-driven epidemiological models: Application to the COVID-19 outbreak in New York City
Epidemiological models can provide the dynamic evolution of a pandemic but they are
based on many assumptions and parameters that have to be adjusted over the time the …
based on many assumptions and parameters that have to be adjusted over the time the …
[HTML][HTML] A modified PINN Approach for Identifiable Compartmental models in Epidemiology with Application to COVID-19
Many approaches using compartmental models have been used to study the COVID-19
pandemic, with machine learning methods applied to these models having particularly …
pandemic, with machine learning methods applied to these models having particularly …
Temporal dynamics and interplay of transmission rate, vaccination, and mutation in epidemic modeling: A poisson point process approach
One of the significant challenges when a new virus circulates in a host population is to
detect the outbreak as it arises in a timely fashion and implement the appropriate preventive …
detect the outbreak as it arises in a timely fashion and implement the appropriate preventive …
System identifiability in a time-evolving agent-based model
Mathematical models are a valuable tool for studying and predicting the spread of infectious
agents. The accuracy of model simulations and predictions invariably depends on the …
agents. The accuracy of model simulations and predictions invariably depends on the …
On the origins and rarity of locally but not globally identifiable parameters in biological modeling
Structural identifiability determines the possibility of estimating the parameters of a model by
observing its output in an ideal experiment. If a parameter is structurally locally identifiable …
observing its output in an ideal experiment. If a parameter is structurally locally identifiable …
Why controlling the asymptomatic infection is important: A modelling study with stability and sensitivity analysis
J Pan, Z Chen, Y He, T Liu, X Cheng, J **ao… - Fractal and …, 2022 - mdpi.com
The large proportion of asymptomatic patients is the major cause leading to the COVID-19
pandemic which is still a significant threat to the whole world. A six-dimensional ODE system …
pandemic which is still a significant threat to the whole world. A six-dimensional ODE system …