Genomic analysis has demonstrated that many fungi possess essential gene clusters for the
production of previously unobserved secondary metabolites; however, these genes are …

Filamentous fungi are one of the most important producers of secondary metabolites. Some
of them can have a toxic effect on the human body, leading to diseases. On the other hand …

Secondary metabolism is one of the important mechanisms by which fungi adapt to their
living environment and promote survival and reproduction. Recent studies have shown that …

The histone acetylation modification is a conservative post-translational epigenetic
regulation in fungi. It includes acetylation and deacetylation at the lysine residues of histone …

Recent advancements in genome sequencing and bioinformatic analysis of fungal genomes
have revealed that fungi possess cryptic or silent biosynthetic gene clusters (BGCs). This …

Natural products have been playing an indispensable role in drug discovery. However, it
seems that the golden period of discovering new compounds has passed since the first …

Monascus spp. can produce a variety of beneficial metabolites widely used in food and
pharmaceutical industries. However, some Monascus species contain the complete gene …

Abscisic acid (ABA) is a conserved and important “sesquiterpene signaling molecule” widely
distributed in different organisms with unique biological functions. ABA coordinates …

Evolutionary novelty has been one of the central themes in the field of evolutionary biology
for many years. Structural and functional innovations such as scales in the reptiles, fins in …

Aromatic amino acids and their derivatives are high value chemicals widely used in food,
pharmaceutical and feed industries. Current preparation methods for aromatic amino acid …