Non-peptide arginine-vasopressin antagonists: the vaptans

G Decaux, A Soupart, G Vassart - The Lancet, 2008 - thelancet.com
Arginine-vasopressin is a hormone that plays an important part in circulatory and water
homoeostasis. The three arginine-vasopressin-receptor subtypes—V1a, V1b, and V2—all …

Acid–base and electrolyte abnormalities in heart failure: pathophysiology and implications

C Urso, S Brucculeri, G Caimi - Heart failure reviews, 2015 - Springer
Electrolyte and acid–base abnormalities are a frequent and potentially dangerous
complication in subjects with congestive heart failure. This may be due either to the …

Tolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for Hyponatremia

RW Schrier, P Gross, M Gheorghiade… - … England Journal of …, 2006 - Mass Medical Soc
Background Hyponatremia (serum sodium concentration,< 135 mmol per liter) is a predictor
of death among patients with chronic heart failure and cirrhosis. At present, therapy for acute …

Hypochloraemia is strongly and independently associated with mortality in patients with chronic heart failure

JM Testani, JS Hanberg, JP Arroyo… - European journal of …, 2016 - Wiley Online Library
Aims Hyponatraemia is strongly associated with adverse outcomes in heart failure.
However, accumulating evidence suggests that chloride may play an important role in renal …

Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension

PR Forfia, SC Mathai, MR Fisher… - American journal of …, 2008 - atsjournals.org
Rationale: Hyponatremia is associated with decompensated heart failure and poor
prognosis in patients with left ventricular systolic dysfunction. Objectives: We sought to …

Multicenter, randomized, double-blind, placebo-controlled study on the effect of oral tolvaptan on left ventricular dilation and function in patients with heart failure and …

JE Udelson, FA McGrew, E Flores, H Ibrahim… - Journal of the American …, 2007 - jacc.org
Objectives: This study sought to examine the effects of vasopressin V2receptor antagonism
with tolvaptan on the changes in left ventricular (LV) volumes over time. Background …

Hyponatremia and in-hospital mortality in patients admitted for heart failure (from the ATTEND registry)

N Sato, M Gheorghiade, K Kajimoto… - The American journal of …, 2013 - Elsevier
Hyponatremia is known to be a poor prognostic factor in patients hospitalized with heart
failure (HF), however not well studied in Japan. The aims of this study were to characterize …

[HTML][HTML] Hyponatremia in patients with heart failure

TD Filippatos, MS Elisaf - World journal of cardiology, 2013 - ncbi.nlm.nih.gov
The present review analyses the mechanisms relating heart failure and hyponatremia,
describes the association of hyponatremia with the progress of disease and …

Electrolyte and acid-base disorders in cancer patients and its impact on clinical outcomes: evidence from a real-world study in China

Y Li, X Chen, Z Shen, Y Wang, J Hu, J Xu, B Shen… - Renal …, 2020 - Taylor & Francis
Background This study aims to delineate the incidence of electrolyte and acid-base
disorders (EAD) in cancer patients, to figure out the risk factors of EAD, then to assess the …

Prognostic significance of hyponatremia among ambulatory patients with heart failure and preserved and reduced ejection fractions

C Bavishi, S Ather, A Bambhroliya, H Jneid… - The American journal of …, 2014 - Elsevier
Hyponatremia in heart failure (HF) is an established predictor of adverse outcomes in
hospitalized patients with reduced ejection fraction (EF). However, there is a paucity of data …