Microwave-induced in situ amorphization: A new strategy for tackling the stability issue of amorphous solid dispersions

W Qiang, K Löbmann, CP McCoy, GP Andrews… - Pharmaceutics, 2020 - mdpi.com
The thermodynamically unstable nature of amorphous drugs has led to a persistent stability
issue of amorphous solid dispersions (ASDs). Lately, microwave-induced in situ …

Development of a Solid Dispersion of Nystatin with Maltodextrin as a Carrier Agent: Improvements in Antifungal Efficacy against Candida spp. Biofilm Infections

C Benavent, C Torrado-Salmerón, S Torrado-Santiago - Pharmaceuticals, 2021 - mdpi.com
The aim of this study was to improve the treatment of Candida albicans biofilms through the
use of nystatin solid dispersions developed using maltodextrins as a hyperosmotic carrier …

Solid dispersions of anthelmintics and plant protection preparations

SS Khalikov - Solids, 2021 - mdpi.com
Because of the rapid development of nanotechnologies, materials, in particular, solid
dispersions (SDs), which are actively introduced into the life of modern man, have been …

[PDF][PDF] Solid Dispersions As Strategy To Improve Solubility And Dissolution Rate Of Water Insoluble Drugs

J Chunduru, P Chadalawada - World Journal …, 2024 - wjpr.s3.ap-south-1.amazonaws.com
Solid dispersions represent a pivotal advancement in pharmaceutical formulation, designed
to address challenges posed by poorly watersoluble drugs. These formulations involve the …

Enhanced Efficacy of Carvedilol by Utilization of Solid Dispersion and Other Novel Strategies: A Review

L Rao, BY Bhardwaj, M Chugh… - … Current Drug Targets …, 2023 - ingentaconnect.com
Carvedilol is classified as a second class drug of Biopharmaceutical classification system
(BCS), and it is an excellent beta blocker and vasodilating agent. It is used in a diverse …

Review on: Solubility enhancement of poorly water soluble drugs

MH Markad, SD Mankar - 2022 - indianjournals.com
About 40% of newly discovered chemicals are lipophilic, and because of their poor solubility
in water they are unable to reach the market due to their solubility in water. Solubility is one …

[PDF][PDF] Mechanochemical technology for regulation of the solubility of anthelmintic drugs by using polymers

SS Khalikov - INEOS OPEN, 2021 - ineosopen.org
Controlling the solubility of poorly water-soluble drugs remains one of the major challenges
in the development of new effective drugs. The use of polymers is one of the promising …

[PDF][PDF] SOLUBILITY ENHANCEMENT: A COMPREHENSIVE REVIEW

SK Yadav, B Yadav, MK Gupta, S Mishra - 2023 - wjpr.s3.ap-south-1.amazonaws.com
Solubility enhancement plays a crucial role in the formulation and development of
pharmaceuticals, as poorly water-soluble drugs often face challenges related to …

Solid Dispersion: Recapitulation

AG Galam, SR Shahi, S Deore… - Asian Journal of …, 2020 - indianjournals.com
The approach to improve dissolution rate of hydrophobic drug and enhance the
bioavailability, solid dispersion is one of the promising approaches in which dispersion of …

[PDF][PDF] Further exploring the pharmaceutical applications of novel microwave-induced in situ amorphization

W Qiang - 2022 - pure.qub.ac.uk
Microwave-induced in situ amorphization is a novel technology that has been applied to
prepare amorphous solid dispersions (ASDs) immediately prior to administration within final …