Advanced nitric oxide generating nanomedicine for therapeutic applications

Z Wang, A **, Z Yang, W Huang - ACS nano, 2023 - ACS Publications
Nitric oxide (NO), a gaseous transmitter extensively present in the human body, regulates
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …

Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives

X Hu, H Zhang, Y Wang, BC Shiu, JH Lin… - Chemical Engineering …, 2022 - Elsevier
The dramatic increase in drug resistant bacteria resistance to existing conventional
antibiotics poses a great challenge to the effective treatment of infectious diseases …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

A bacteria‐responsive porphyrin for adaptable photodynamic/photothermal therapy

H Hu, H Wang, Y Yang, JF Xu… - Angewandte Chemie …, 2022 - Wiley Online Library
We report a cationic porphyrin 5, 10, 15, 20‐tetrakis‐(4‐N‐methylpyridyl)‐porphyrin (TMPyP)
that can respond to specific bacteria, followed by adaptable photodynamic/photothermal …

An injectable multifunctional hydrogel for eradication of bacterial biofilms and wound healing

T Du, Z **ao, G Zhang, L Wei, J Cao, Z Zhang, X Li… - Acta biomaterialia, 2023 - Elsevier
Wound treatment is largely influenced by pre-existing hypoxic microenvironments and
biofilms, which can severely diminish the efficacy of phototherapy, suggesting the …

Near-infrared light-triggered nitric-oxide-enhanced photodynamic therapy and low-temperature photothermal therapy for biofilm elimination

Z Yuan, C Lin, Y He, B Tao, M Chen, J Zhang, P Liu… - ACS …, 2020 - ACS Publications
Photothermal treatment (PTT) involving a combination of therapeutic modalities recently
emerged as an efficient alternative for combating biofilm. However, PTT-related local high …

Transition Metal High‐Entropy Nanozyme: Multi‐Site Orbital Coupling Modulated High‐Efficiency Peroxidase Mimics

J Feng, X Yang, T Du, L Zhang, P Zhang… - Advanced …, 2023 - Wiley Online Library
Strong substrate affinity and high catalytic efficiency are persistently pursued to generate
high‐performance nanozymes. Herein, with unique surface atomic configurations and …

A Self‐Catalytic NO/O2 Gas‐Releasing Nanozyme for Radiotherapy Sensitization through Vascular Normalization and Hypoxia Relief

S Wang, M Cheng, S Wang, W Jiang, F Yang… - Advanced …, 2024 - Wiley Online Library
Radiotherapy (RT), essential for treating various cancers, faces challenges from tumor
hypoxia, which induces radioresistance. A tumor‐targeted “prosthetic‐Arginine” …

Electron donor–acceptor interface of TPPS/PDI boosting charge transfer for efficient photocatalytic hydrogen evolution

J Yang, J **g, W Li, Y Zhu - Advanced Science, 2022 - Wiley Online Library
Charge separation efficiency of photocatalysts is still the key scientific issue for solar‐to‐
chemical energy conversion. In this work, an electron donor–acceptor (D‐A) interface with …

Recent advances of multi-dimensional porphyrin-based functional materials in photodynamic therapy

J Tian, B Huang, MH Nawaz, W Zhang - Coordination Chemistry Reviews, 2020 - Elsevier
Photodynamic therapy (PDT) has emerged as a promising and non-invasive modality for
cancer treatments. Photosensitizers, as one of the essential elements in PDT, play a crucial …