Antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - pmc.ncbi.nlm.nih.gov
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

The structure-mechanism relationship and mode of actions of antimicrobial peptides: A review

S Li, Y Wang, Z Xue, Y Jia, R Li, C He… - Trends in Food Science & …, 2021 - Elsevier
Background The rapid increase of drug resistance in conventional antibiotics promotes the
discovery and development of antimicrobial peptides (AMPs), which are important …

Application of antimicrobial peptides of the innate immune system in combination with conventional antibiotics—a novel way to combat antibiotic resistance?

MS Zharkova, DS Orlov, OY Golubeva… - Frontiers in cellular …, 2019 - frontiersin.org
Rapidly growing resistance of pathogenic bacteria to conventional antibiotics leads to
inefficiency of traditional approaches of countering infections and determines the urgent …

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

KA Brogden - Nature reviews microbiology, 2005 - nature.com
Antimicrobial peptides are an abundant and diverse group of molecules that are produced
by many tissues and cell types in a variety of invertebrate, plant and animal species. Their …

Innate humoral immune defences in mammals and insects: The same, with differences?

G Sheehan, A Garvey, M Croke, K Kavanagh - Virulence, 2018 - Taylor & Francis
The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …

Overview on the recent study of antimicrobial peptides: origins, functions, relative mechanisms and application

Y Li, Q **ang, Q Zhang, Y Huang, Z Su - Peptides, 2012 - Elsevier
Antimicrobial peptides (AMPs), which are produced by several species including insects,
other animals, micro-organisms and synthesis, are a critical component of the natural …

Non-membrane permeabilizing modes of action of antimicrobial peptides on bacteria

M Scocchi, M Mardirossian, G Runti… - Current topics in …, 2016 - ingentaconnect.com
Antimicrobial peptides (AMPs) are a large class of innate immunity effectors with a
remarkable capacity to inactivate microorganisms. Their ability to kill bacteria by …

[HTML][HTML] Tryptophan-rich and proline-rich antimicrobial peptides

AK Mishra, J Choi, E Moon, KH Baek - Molecules, 2018 - mdpi.com
Due to the increasing emergence of drug-resistant pathogenic microorganisms, there is a
world-wide quest to develop new-generation antibiotics. Antimicrobial peptides (AMPs) are …

Inhibition of translation termination by the antimicrobial peptide Drosocin

K Mangano, D Klepacki, I Ohanmu, C Baliga… - Nature chemical …, 2023 - nature.com
The proline-rich antimicrobial peptide (PrAMP) Drosocin (Dro) from fruit flies shows
sequence similarity to other PrAMPs that bind to the ribosome and inhibit protein synthesis …

Insect antimicrobial peptides: structures, properties and gene regulation

P Bulet, R Stocklin - Protein and peptide letters, 2005 - ingentaconnect.com
Antimicrobial peptides (AMPs) are part of the armament that insects have developed to fight
off pathogens. Insect AMPs are typically cationic and often made of less than 100 amino acid …