The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …

Zebrafish (Danio rerio) are rapidly gaining popularity in translational neuroscience and
behavioral research. Physiological similarity to mammals, ease of genetic manipulations …

The new field of" Computational Ethology" is made possible by advances in technology,
mathematics, and engineering that allow scientists to automate the measurement and the …

Although manganese is an essential trace metal, little is known about its transport and
homeostatic regulation. Here we have identified a cohort of patients with a novel autosomal …

Light affects animal physiology and behavior more than simply through classical visual,
image-forming pathways. Nonvisual photoreception regulates numerous biological systems …

Background DYRK1A maps to the Down syndrome critical region at 21q22. Mutations in this
kinase-encoding gene have been reported to cause microcephaly associated with either …

The zebrafish represents an excellent compromise between system complexity and practical
simplicity, features that make it useful for modeling and mechanistic analysis of complex …

Depression is a high-incidence mood disorder that is frequently accompanied by sleep
disturbances, which can be triggered by the non-image-forming (NIF) visual system …

Sleep–wake abnormalities are common in patients with Alzheimer's disease, and can be a
major reason for institutionalization. However, an emerging concept is that these sleep …

The larval zebrafish has emerged as a vertebrate model system amenable to small molecule
screens for probing diverse biological pathways. Two large‐scale small molecule screens …