[HTML][HTML] Antimicrobial resistance in methicillin-resistant Staphylococcus aureus

BA Alghamdi, I Al-Johani, JM Al-Shamrani… - Saudi journal of …, 2023 - Elsevier
In the medical community, antibiotics are revered as a miracle because they stop diseases
brought on by pathogenic bacteria. Antibiotics have become the cornerstone of …

Designing multi-epitope vaccine against Staphylococcus aureus by employing subtractive proteomics, reverse vaccinology and immuno-informatics approaches

MT ul Qamar, S Ahmad, I Fatima, F Ahmad… - Computers in Biology …, 2021 - Elsevier
Staphylococcus aureus is a deadly human bacterial pathogen that causes a wide variety of
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …

Design of a Multi-Epitope Vaccine against Tropheryma whipplei Using Immunoinformatics and Molecular Dynamics Simulation Techniques

TH Albekairi, A Alshammari, M Alharbi, AF Alshammary… - Vaccines, 2022 - mdpi.com
Whipple's disease is caused by T. whipplei, a Gram-positive pathogenic bacterium. It is
considered a persistent infection affecting various organs, more likely to infect males. There …

Proteome-Wide Screening of Potential Vaccine Targets against Brucella melitensis

M Malik, S Khan, A Ullah, M Hassan, M Haq, S Ahmad… - Vaccines, 2023 - mdpi.com
The ongoing antibiotic-resistance crisis is becoming a global problem affecting public
health. Urgent efforts are required to design novel therapeutics against pathogenic bacterial …

Evidence of the efficiency of reverse vaccinology against bovine parasites: a systematic review

BCF Nogueira, NTBS Honório, PE de Almeida Souza… - Acta Tropica, 2024 - Elsevier
Reverse vaccinology is a novel vaccine development technology that uses genome and
proteome analyses through bioinformatics to select antigenic epitopes capable of eliciting …

[HTML][HTML] Development of a candidate multi-epitope vaccine against Sphingobacterium spiritivorum: Reverse vaccinology and immunoinformatics approach

MA Alamri - Saudi Medical Journal, 2023 - ncbi.nlm.nih.gov
Objectives: To develop a candidate vaccine aginst the Sphingobacterium spiritivorum.
Methods: Since there is currently no vaccine against this pathogen, we employed in-silico …

In silico designed Staphylococcus aureus B-cell multi-epitope vaccine did not elicit antibodies against target antigens suggesting multi-domain approach

N Ullah, F Anwer, Z Ishaq, A Siddique, MA Shah… - Journal of …, 2022 - Elsevier
The vaccine development strategies have evolved from using an entire organism as an
immunogen to a single antigen and further towards an epitope. Since an epitope is a …

[HTML][HTML] Average Nucleotide Identity based Staphylococcus aureus strain grou** allows identification of strain-specific genes in the pangenome

V Raghuram, RA Petit III, Z Karol, R Mehta… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Staphylococcus aureus causes both hospital and community acquired infections in humans
worldwide. Due to the high incidence of infection S. aureus is also one of the most sampled …

[PDF][PDF] Design of a Multi-Epitope Vaccine against Tropheryma whipplei Using Immunoinformatics and Molecular Dynamics Simulation Techniques. Vaccines 2022, 10 …

TH Albekairi, A Alshammari, M Alharbi, AF Alshammary… - 2022 - academia.edu
Whipple's disease is caused by T. whipplei, a Gram-positive pathogenic bacterium. It is
considered a persistent infection affecting various organs, more likely to infect males. There …

[PDF][PDF] Proteome-wide Screening of Potential Vaccine Targets against Brucella melitensis. Vaccines 2023, 11, 263

M Malik, S Khan, A Ullah, M Hassan, M Haq, S Ahmad… - 2023 - researchgate.net
The ongoing antibiotic-resistance crisis is becoming a global problem affecting public
health. Urgent efforts are required to design novel therapeutics against pathogenic bacterial …