Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …
Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …
associated complications. The imbalance between reactive oxygen species (ROS) …
The reduction in the mitochondrial membrane potential in aging: the role of the mitochondrial permeability transition pore
H Rottenberg - International Journal of Molecular Sciences, 2023 - mdpi.com
It is widely reported that the mitochondrial membrane potential,∆ Ψm, is reduced in aging
animals. It was recently suggested that the lower∆ Ψm in aged animals modulates …
animals. It was recently suggested that the lower∆ Ψm in aged animals modulates …
Oxidative stress factors mediate the association between life's essential 8 and accelerated phenotypic aging: NHANES 2005–2018
W Liu, J Wang, M Wang, H Hou, X Ding… - The Journals of …, 2024 - academic.oup.com
Cardiovascular health (CVH) is a well-known predictor of morbidity and mortality, while
phenotypic age (PhenoAge) is a promising biomarker of aging. This study aimed to explore …
phenotypic age (PhenoAge) is a promising biomarker of aging. This study aimed to explore …
Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …
[HTML][HTML] Oxidative stress and age-related tumors
E Di Carlo, C Sorrentino - Antioxidants, 2024 - pmc.ncbi.nlm.nih.gov
Oxidative stress is the result of the imbalance between reactive oxygen and nitrogen species
(RONS), which are produced by several endogenous and exogenous processes, and …
(RONS), which are produced by several endogenous and exogenous processes, and …
Human diet‐derived polyphenolic compounds and hepatic diseases: From therapeutic mechanisms to clinical utilization
Q Hu, W Zhang, F Wei, M Huang, M Shu… - Phytotherapy …, 2024 - Wiley Online Library
This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
[HTML][HTML] Pharmacotherapeutic considerations on telomere biology: The positive effect of pharmacologically active substances on telomere length
Telomeres are part of chromatin structures containing repeated DNA sequences, which
function as protective caps at the ends of chromosomes and prevent DNA degradation and …
function as protective caps at the ends of chromosomes and prevent DNA degradation and …
Targeting the redox system for cardiovascular regeneration in aging
Cardiovascular aging presents a formidable challenge, as the aging process can lead to
reduced cardiac function and heightened susceptibility to cardiovascular diseases …
reduced cardiac function and heightened susceptibility to cardiovascular diseases …
[HTML][HTML] Canagliflozin Inhibits Palmitic Acid-Induced Vascular Cell Aging In Vitro through ROS/ERK and Ferroptosis Pathways
F Wan, X He, W **e - Antioxidants, 2024 - mdpi.com
Vascular aging is one of the reasons for the high incidence of cardiovascular diseases
nowadays, as vascular cells age due to various internal and external factors. Among them …
nowadays, as vascular cells age due to various internal and external factors. Among them …