Orthologs, paralogs, and evolutionary genomics

EV Koonin - Annu. Rev. Genet., 2005 - annualreviews.org
Orthologs and paralogs are two fundamentally different types of homologous genes that
evolved, respectively, by vertical descent from a single ancestral gene and by duplication …

Netting the stress responses in fish

JC Balasch, L Tort - Frontiers in Endocrinology, 2019 - frontiersin.org
In the last decade, the concept of animal stress has been stressed thin to accommodate the
effects of short-term changes in cell and tissue physiology, major behavioral syndromes in …

[HTML][HTML] Pan-genome of wild and cultivated soybeans

Y Liu, H Du, P Li, Y Shen, H Peng, S Liu, GA Zhou… - Cell, 2020 - cell.com
Soybean is one of the most important vegetable oil and protein feed crops. To capture the
entire genomic diversity, it is needed to construct a complete high-quality pan-genome from …

Extreme expansion of the olfactory receptor gene repertoire in African elephants and evolutionary dynamics of orthologous gene groups in 13 placental mammals

Y Niimura, A Matsui, K Touhara - Genome research, 2014 - genome.cshlp.org
Olfactory receptors (ORs) detect odors in the environment, and OR genes constitute the
largest multigene family in mammals. Numbers of OR genes vary greatly among species …

An integrated view of protein evolution

C Pál, B Papp, MJ Lercher - Nature reviews genetics, 2006 - nature.com
Why do proteins evolve at different rates? Advances in systems biology and genomics have
facilitated a move from studying individual proteins to characterizing global cellular factors …

Identification of shared single copy nuclear genes in Arabidopsis, Populus, Vitis and Oryzaand their phylogenetic utility across various taxonomic levels

JM Duarte, PK Wall, PP Edger, LL Landherr… - BMC evolutionary …, 2010 - Springer
Background Although the overwhelming majority of genes found in angiosperms are
members of gene families, and both gene-and genome-duplication are pervasive forces in …

Gene loss and evolutionary rates following whole-genome duplication in teleost fishes

FG Brunet, HR Crollius, M Paris, JM Aury… - Molecular biology …, 2006 - academic.oup.com
Teleost fishes provide the first unambiguous support for ancient whole-genome duplication
in an animal lineage. Studies in yeast or plants have shown that the effects of such …

Gene duplication: a drive for phenotypic diversity and cause of human disease

B Conrad, SE Antonarakis - Annu. Rev. Genomics Hum. Genet., 2007 - annualreviews.org
Gene duplication is one of the key factors driving genetic innovation, ie, producing novel
genetic variants. Although the contribution of whole-genome and segmental duplications to …

A catalog of neutral and deleterious polymorphism in yeast

SW Doniger, HS Kim, D Swain, D Corcuera… - PLoS …, 2008 - journals.plos.org
The abundance and identity of functional variation segregating in natural populations is
paramount to dissecting the molecular basis of quantitative traits as well as human genetic …

Paleopolyploidy and gene duplication in soybean and other legumes

RC Shoemaker, J Schlueter, JJ Doyle - Current opinion in plant biology, 2006 - Elsevier
Two of the most important observations from whole-genome sequences have been the high
rate of gene birth and death and the prevalence of large-scale duplication events, including …