[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

[HTML][HTML] Cryogenic electron microscopy methodologies as analytical tools for the study of self-assembled pharmaceutics

N Koifman, Y Talmon - Pharmaceutics, 2021 - mdpi.com
Many pharmaceutics are aqueous dispersions of small or large molecules, often self-
assembled in complexes from a few to hundreds of molecules. In many cases, the …

Unraveling multilayered extracellular vesicles: Speculation on cause

K Broad, SA Walker, I Davidovich… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐released, heterogenous nanoparticles that play
important roles in (patho) physiological processes through intercellular communication. EVs …

The extracellular vesicle proteomes of Sorghum bicolor and Arabidopsis thaliana are partially conserved

T Chaya, A Banerjee, BD Rutter, D Adekanye… - Plant …, 2024 - academic.oup.com
Plant extracellular vesicles (EVs) are membrane-bound organelles involved mainly in
intercellular communications and defense responses against pathogens. Recent studies …

Free-standing DNA origami superlattice to facilitate cryo-EM visualization of membrane vesicles

N Aissaoui, A Mills, J Lai-Kee-Him… - Journal of the …, 2024 - ACS Publications
Technological breakthroughs in cryo-electron microscopy (cryo-EM) methods open new
perspectives for highly detailed structural characterizations of extracellular vesicles (EVs) …

Autolysosomal exocytosis of lipids protect neurons from ferroptosis

I Ralhan, J Chang, MJ Moulton, LD Goodman… - Journal of Cell …, 2023 - rupress.org
During oxidative stress neurons release lipids that are internalized by glia. Defects in this
coordinated process play an important role in several neurodegenerative diseases. Yet, the …

Endothelial cells release microvesicles that harbour multivesicular bodies and secrete exosomes

JD Petersen, E Mekhedov, S Kaur… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) released by endothelial cells support vascular homeostasis. To
better understand endothelial cell EV biogenesis, we examined cultured human umbilical …

HIV‐1 Nef is carried on the surface of extracellular vesicles

C Vanpouille, B Brichacek, T Pushkarsky… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) serve as pivotal mediators of intercellular communication in both
health and disease, delivering biologically active molecules from vesicle‐producing cells to …

Cryopreservation of mesenchymal stromal cell-derived extracellular vesicles using trehalose maintains their ability to expand hematopoietic stem cells in vitro

P Budgude, V Kale, A Vaidya - Cryobiology, 2021 - Elsevier
The multitude of clinical trials using mesenchymal stromal cells (MSCs) has underscored
their significance as a promising cell source for regenerative therapies. Most studies have …

Emerging role of extracellular vesicles in multiple sclerosis: From cellular surrogates to pathogenic mediators and beyond

PL Palacio, ML Pleet, E Reátegui… - Journal of …, 2023 - Elsevier
Multiple Sclerosis (MS) is a chronic, inflammatory demyelinating disease of the central
nervous system (CNS) driven by a complex interplay of genetic and environmental factors …