Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …

Traditional destructive tests are used for quality assurance and control within manufacturing
workflows. Their applicability to biomanufacturing is limited due to inherent constraints of the …

We report the design, development, and characterization of a novel multi-spectral
fluorescence lifetime measurement device incorporating solid-state detectors and …

Conjugated oligoelectrolytes (COEs) comprise a class of cell‐membrane intercalating
molecules that serve as effective optical reporters. However, little is known about the …

Articular cartilage injuries are a common source of joint pain and dysfunction. As articular
cartilage is avascular, it exhibits a poor intrinsic healing capacity for self-repair. Clinically …

Cartilage demineralisation in Osteoarthritis (OA) patients can elevate calcium ion levels in
synovial fluid, as evidenced by the prevalence of precipitated calcium phosphate crystals in …

Osteoarthritis (OA) is the most common arthritis and its hallmark is degradation of articular
cartilage by proteolytic enzymes leading to loss of joint function. It is challenging to monitor …

Background: Clinical trials are currently underway to investigate the efficacy of intra-articular
administration of mesenchymal stromal cells (MSCs) to mitigate osteoarthritis (OA) …

This narrative review provides an overview of the various diagnostic tools used to assess
cartilage health, with a focus on early detection, nutrition intervention, and management of …

Tissue engineers rely on expensive, time‐consuming, and destructive techniques to monitor
the composition, microstructure, and function of engineered tissue equivalents. A non …