Ischemia reperfusion injury, ischemic conditioning and diabetes mellitus

A Lejay, F Fang, R John, JAD Van, M Barr… - Journal of Molecular and …, 2016 - Elsevier
Ischemia/reperfusion, which is characterized by deficient oxygen supply and subsequent
restoration of blood flow, can cause irreversible damages to tissue. Mechanisms contributing …

Acute kidney injury overview: from basic findings to new prevention and therapy strategies

SR Gonsalez, AL Cortês, RC da Silva, J Lowe… - Pharmacology & …, 2019 - Elsevier
Acute kidney injury (AKI) is defined as a decrease in kidney function within hours, which
encompasses both injury and impairment of renal function. AKI is not considered a …

The role of mitochondrial reactive oxygen species in cardiovascular injury and protective strategies

DM Muntean, A Sturza, MD Dănilă… - Oxidative medicine …, 2016 - Wiley Online Library
Ischaemia/reperfusion (I/R) injury of the heart represents a major health burden mainly
associated with acute coronary syndromes. While timely coronary reperfusion has become …

Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury

K Moskowitzova, A Orfany, K Liu… - … of Physiology-Lung …, 2020 - journals.physiology.org
The most common cause of acute lung injury is ischemia-reperfusion injury (IRI), during
which mitochondrial damage occurs. We have previously demonstrated that mitochondrial …

Oxidative stress induced osteocyte apoptosis in steroid‐induced femoral head necrosis

ZQ Fan, SC Bai, Q Xu, ZJ Li, WH Cui, H Li… - Orthopaedic …, 2021 - Wiley Online Library
Objective To investigate the effect and mechanism of Glucocorticoids (GCs) induced
oxidative stress and apoptosis on necrosis of the femoral head in patients and rats. Methods …

Mitochondria-inspired nanoparticles with microenvironment-adapting capacities for on-demand drug delivery after ischemic injury

Y Lin, J Liu, R Bai, J Shi, X Zhu, J Liu, J Guo, W Zhang… - ACS …, 2020 - ACS Publications
Stimuli-responsive nanoparticles (NPs), so-called “smart” NPs, possess great potentials in
drug delivery. Presently, the intelligence of smart NPs is mainly based on their chemical or …

Potential Harmful Effects of PM2.5 on Occurrence and Progression of Acute Coronary Syndrome: Epidemiology, Mechanisms, and Prevention Measures

X Meng, Y Zhang, KQ Yang, YK Yang… - International journal of …, 2016 - mdpi.com
The harmful effects of particulate matter with an aerodynamic diameter of< 2.5 µm (PM2. 5)
and its association with acute coronary syndrome (ACS) has gained increased attention in …

Oxy-nitroso shielding burst model of cold atmospheric plasma therapeutics

DB Graves - Clinical Plasma Medicine, 2014 - Elsevier
It is postulated that cold atmospheric plasma (CAP) can trigger a therapeutic shielding
response in tissue by creating a time-and space-localized, burst-like form of oxy-nitrosative …

Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets

T Wang, C Gross, AA Desai… - … of Physiology-Lung …, 2017 - journals.physiology.org
Mechanical ventilation is a life-saving intervention in critically ill patients with respiratory
failure due to acute respiratory distress syndrome (ARDS). Paradoxically, mechanical …

Neuroprotective potential of mild uncoupling in mitochondria. Pros and cons

DB Zorov, NV Andrianova, VA Babenko, IB Pevzner… - Brain Sciences, 2021 - mdpi.com
There has been an explosion of interest in the use of uncouplers of oxidative
phosphorylation in mitochondria in the treatment of several pathologies, including …