Variable host–pathogen compatibility in Mycobacterium tuberculosis

S Gagneux, K DeRiemer, T Van, M Kato-Maeda… - Proceedings of the …, 2006 - pnas.org
Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide.
Studies have reported human pathogens to have geographically structured population …

The Influence of Host and Bacterial Genotype on the Development of Disseminated Disease with Mycobacterium tuberculosis

M Caws, G Thwaites, S Dunstan, TR Hawn… - PLoS …, 2008 - journals.plos.org
The factors that govern the development of tuberculosis disease are incompletely
understood. We hypothesized that some strains of Mycobacterium tuberculosis (M …

Genoty** of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies

I Comas, S Homolka, S Niemann, S Gagneux - PloS one, 2009 - journals.plos.org
Because genetically monomorphic bacterial pathogens harbour little DNA sequence
diversity, most current genoty** techniques used to study the epidemiology of these …

Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis

S Gagneux, MV Burgos, K DeRiemer, A Enciso… - PLoS …, 2006 - journals.plos.org
Understanding the ecology of drug-resistant pathogens is essential for devising rational
programs to preserve the effective lifespan of antimicrobial agents and to abrogate …

The burden of mycobacterial disease in Ethiopian cattle: implications for public health

S Berg, R Firdessa, M Habtamu, E Gadisa, A Mengistu… - PloS one, 2009 - journals.plos.org
Background Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a debilitating
disease of cattle. Ethiopia has one of the largest cattle populations in the world, with an …

Significance of the Identification in the Horn of Africa of an Exceptionally Deep Branching Mycobacterium tuberculosis Clade

Y Blouin, Y Hauck, C Soler, M Fabre, R Vong… - PloS one, 2012 - journals.plos.org
Molecular and phylogeographic studies have led to the definition within the Mycobacterium
tuberculosis complex (MTBC) of a number of geotypes and ecotypes showing a preferential …

Genomic Diversity among Drug Sensitive and Multidrug Resistant Isolates of Mycobacterium tuberculosis with Identical DNA Fingerprints

S Niemann, CU Köser, S Gagneux, C Plinke… - PloS one, 2009 - journals.plos.org
Background Mycobacterium tuberculosis complex (MTBC), the causative agent of
tuberculosis (TB), is characterized by low sequence diversity making this bacterium one of …

Reference set of Mycobacterium tuberculosis clinical strains: A tool for research and product development

S Borrell, A Trauner, D Brites, L Rigouts, C Loiseau… - PLoS one, 2019 - journals.plos.org
The Mycobacterium tuberculosis complex (MTBC) causes tuberculosis (TB) in humans and
various other mammals. The human-adapted members of the MTBC comprise seven …

The chosen few: Mycobacterium tuberculosis isolates for IMPAc-TB

SE Larsen, HFM Abdelaal, CR Plumlee… - Frontiers in …, 2024 - frontiersin.org
The three programs that make up the Immune Mechanisms of Protection Against
Mycobacterium tuberculosis Centers (IMPAc-TB) had to prioritize and select strains to be …

Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response

J Carmona, A Cruz, L Moreira-Teixeira, C Sousa… - PloS one, 2013 - journals.plos.org
Tuberculosis associates with a wide spectrum of disease outcomes. The Bei**g (Bj) lineage
of Mycobacterium tuberculosis (Mtb) is suggested to be more virulent than other Mtb …