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Optogenetics for light control of biological systems
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
Improved tools to study astrocytes
Astrocytes are a type of glial cell that tile the CNS. They interact with multiple cell types,
including neurons, glial cells and blood vessels, and are involved or implicated in brain …
including neurons, glial cells and blood vessels, and are involved or implicated in brain …
Optogenetic tools for subcellular applications in neuroscience
The ability to study cellular physiology using photosensitive, genetically encoded molecules
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …
Melanopsin and the intrinsically photosensitive retinal ganglion cells: biophysics to behavior
MTH Do - Neuron, 2019 - cell.com
The mammalian visual system encodes information over a remarkable breadth of
spatiotemporal scales and light intensities. This performance originates with its complement …
spatiotemporal scales and light intensities. This performance originates with its complement …
Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin
Information is carried between brain regions through neurotransmitter release from axonal
presynaptic terminals. Understanding the functional roles of defined neuronal projection …
presynaptic terminals. Understanding the functional roles of defined neuronal projection …
[HTML][HTML] Optogenetics for visual restoration: from proof of principle to translational challenges
Degenerative retinal disorders are a diverse family of diseases commonly leading to
irreversible photoreceptor death, while leaving the inner retina relatively intact. Over recent …
irreversible photoreceptor death, while leaving the inner retina relatively intact. Over recent …
Nano-optogenetics for disease therapies
Q Lu, Y Sun, Z Liang, Y Zhang, Z Wang, Q Mei - ACS nano, 2024 - ACS Publications
Optogenetic, known as the method of 21 centuries, combines optic and genetic engineering
to precisely control photosensitive proteins for manipulation of a broad range of cellular …
to precisely control photosensitive proteins for manipulation of a broad range of cellular …
Optophysiology: Illuminating cell physiology with optogenetics
Optogenetics combines light and genetics to enable precise control of living cells, tissues,
and organisms with tailored functions. Optogenetics has the advantages of …
and organisms with tailored functions. Optogenetics has the advantages of …
Selective optogenetic control of Gq signaling using human Neuropsin
A Wagdi, D Malan, U Sathyanarayanan… - Nature …, 2022 - nature.com
Gq proteins are universally important for signal transduction in mammalian cells. The
underlying kinetics and transformation from extracellular stimuli into intracellular signaling …
underlying kinetics and transformation from extracellular stimuli into intracellular signaling …
Neurophotonic tools for microscopic measurements and manipulation: status report
Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …
focused on development of technologies for advancement of neuroscience. For the last …