Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

YN Zhang, W Poon, AJ Tavares, ID McGilvray… - Journal of controlled …, 2016 - Elsevier
99% of administered nanoparticles will accumulate and sequester in the liver after
administration into the body. This results in reduced delivery to the targeted diseased tissue …

Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications

LH Reddy, JL Arias, J Nicolas, P Couvreur - Chemical reviews, 2012 - ACS Publications
In recent years, considerable efforts have been spent in the development of magnetic
nanoparticles (MNPs), the understanding of their behavior, and the improvement of their …

Asialoglycoprotein receptor mediated hepatocyte targeting—Strategies and applications

AA D'Souza, PV Devarajan - Journal of controlled release, 2015 - Elsevier
Hepatocyte resident afflictions continue to affect the human population unabated. The
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …

[HTML][HTML] Recent advances in engineering iron oxide nanoparticles for effective magnetic resonance imaging

Z Zhao, M Li, J Zeng, L Huo, K Liu, R Wei, K Ni, J Gao - Bioactive Materials, 2022 - Elsevier
Iron oxide nanoparticle (IONP) with unique magnetic property and high biocompatibility
have been widely used as magnetic resonance imaging (MRI) contrast agent (CA) for long …

Potential applications of enzymes immobilized on/in nano materials: A review

SA Ansari, Q Husain - Biotechnology advances, 2012 - Elsevier
Several new types of carriers and technologies have been implemented in the recent past to
improve traditional enzyme immobilization which aimed to enhance enzyme loading, activity …

A hepatocyte-targeting nanoparticle for enhanced hepatobiliary magnetic resonance imaging

H Zhang, Y Guo, J Jiao, Y Qiu, Y Miao, Y He… - Nature biomedical …, 2023 - nature.com
Hepatobiliary magnetic resonance imaging (MRI) can inform the diagnosis of liver tumours
in patients with liver cirrhosis and hepatitis. However, its clinical utility has been hampered …

Functionalisation of nanoparticles for biomedical applications

NTK Thanh, LAW Green - Nano today, 2010 - Elsevier
Nanoparticles with cores composed of inorganic materials such as noble, magnetic metals,
their alloys and oxides, and semiconductors have been most studied and have vast potential …

Perspective of Fe3O4 Nanoparticles Role in Biomedical Applications

MR Ghazanfari, M Kashefi, SF Shams… - Biochemistry …, 2016 - Wiley Online Library
In recent years, although many review articles have been presented about bioapplications of
magnetic nanoparticles by some research groups with different expertise such as chemistry …

Applications of nanobiomaterials in the therapy and imaging of acute liver failure

Y **, H Wang, K Yi, S Lv, H Hu, M Li, Y Tao - Nano-micro letters, 2021 - Springer
Highlights This review focuses on the therapeutic mechanisms, targeting strategies of
various nanomaterials in acute liver failure, and recent advances of diverse nanomaterials …

Carbohydrate nanocarriers in biomedical applications: functionalization and construction

B Kang, T Opatz, K Landfester, FR Wurm - Chemical Society Reviews, 2015 - pubs.rsc.org
The specific targeting of either tumor cells or immune cells in vivo by carefully designed and
appropriately surface-functionalized nanocarriers may become an effective therapeutic …