This review summarizes advances in the chemistry of acridines concerning properties,
isolation of natural products possessing the acridine ring as a partial structure, new …

Thiazacridine and imidazacridine derivatives have shown promising results as tumors
suppressors in some cancer cell lines. For a better understanding of the mechanism of …

The ability to intercalate between DNA strands determines the cytotoxic activity of numerous
anticancer drugs. Strikingly, intercalating activity was also reported for some compounds …

Three new diphenylsubstituted spirotriazolidine-and thiazolidinone⿿ acridines were
prepared and their interaction with calf thymus DNA investigated with UV⿿ vis …

G-Quadruplex DNA (GQ–DNA) is one of the most important non-canonical nucleic acid
structures. GQ–DNA forming sequences are present in different crucial genomic regions and …

Studies on the intercalation of anticancer compounds with DNA can provide useful
suggestions and guidance for the design of new and more efficient anticancer drugs. A …

Objective Oleanolic acid (OA) has been reported to have anticancer effects, but the extent of
its cytotoxicity, its ability to interact with nuclear DNA, its action against skin melanoma, as …

RNA plays an important role in many biological processes which are crucial for cell survival,
and it has been suggested that it may be possible to inhibit individual processes involved in …

Acridine derivatives represent a well-known class of anticancer agents that generally
interfere with DNA synthesis and inhibit topoisomerase II. A series of eight new 3-acridin-9 …

Several acridine derivatives have been screened for their therapeutic potential and some
are already established as antiprotozoan, antibacterial or anticancer agents. However …