Stress is viewed as a state of real or perceived threat to homeostasis, the management of
which involves the endocrine, nervous, and immune systems. These systems work …

Over the years, the vaste expansion of plastic manufacturing has dramatically increased the
environmental impact of microplastics [MPs] and nanoplastics [NPs], making them a threat to …

Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

Chronic sleep deprivation has been demonstrated to diminish cognitive performance, alter
mood states, and concomitantly dysregulate inflammation and stress hormones. At present …

Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The
pathogenesis of MDD remained unclear, and it may be associated with exposure to different …

Emerging evidence indicates that ingestion of specific probiotics, known as “psychobiotics”,
confer beneficial effects on mental health. This study investigated antidepressant-like effects …

The corticotropin-releasing hormone cells in the paraventricular nucleus of the
hypothalamus (CRH PVN) control the slow endocrine response to stress. The synapses on …

An organism's capacity to cope with stressful experiences is dependent on its ability to
appropriately engage central and peripheral systems, such as the hypothalamic-pituitary …

Serotonin (5-HT) is a critical player in brain development and neuropsychiatric disorders.
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …

The anesthetic-surgical stress response consists of metabolic, neuroendocrine,
hemodynamic, immunological, and behavioral adaptations through chemical mediators …