The murine models of Alzheimer's disease (AD) have advanced our understanding of the
pathophysiology. In vivo studies of the retina using optical coherence tomography (OCT) …

Significance: As one part of the central nervous system, the retina manifests neurovascular
defects in Alzheimer's disease (AD). Quantitative imaging of retinal neurovascular …

The ocular vasculature is critically involved in many blinding diseases and is also a popular
research model for the exploration of developmental and pathological angiogenesis. The …

Animal models of disease are paramount to understand retinal development, the
pathophysiology of eye diseases, and to study neurodegeneration using optical coherence …

In Alzheimer's disease (AD), transgenic mouse models have established links between
abnormalities in the retina and those in the brain. APPNL-F/NL-F is a murine, humanized AD …

Differential artery-vein (AV) analysis is essential for retinal study, disease detection, and
treatment assessment. This study is to characterize vascular reflectance profiles and blood …

Regenerative translational studies must include a longitudinal assessment of the changes in
retinal structure and function that occur as part of the natural history of the disease and those …

The growth of the mouse eye and retina after birth is a dynamic, highly regulated process. In
this study, we applied visible-light optical coherence tomography (vis-OCT), a non-invasive …

Featured Application Quantitative optical coherence tomography (OCT) promises a
noninvasive method for longitudinal monitoring of postnatal retinal development. Abstract A …

Mice are widely used as models for many diseases, including eye and neurodegenerative
diseases. However, there is a lack of normative data for retinal thickness over time …