Aggression, social stress, and the immune system in humans and animal models

A Takahashi, ME Flanigan, BS McEwen… - Frontiers in Behavioral …, 2018‏ - frontiersin.org
Social stress can lead to the development of psychological problems ranging from
exaggerated anxiety and depression to antisocial and violence-related behaviors …

Organization of neural circuits underlying social behavior: A consideration of the medial amygdala

T Raam, W Hong - Current opinion in neurobiology, 2021‏ - Elsevier
The medial amygdala (MeA) is critical for the expression of a broad range of social
behaviors, and is also connected to many other brain regions that mediate those same …

[HTML][HTML] Responses and functions of dopamine in nucleus accumbens core during social behaviors

B Dai, F Sun, X Tong, Y Ding, A Kuang, T Osakada… - Cell reports, 2022‏ - cell.com
Social behaviors are among the most important motivated behaviors. How dopamine (DA),
a" reward" signal, releases during social behaviors has been a topic of interest for decades …

Simple Behavioral Analysis (SimBA)–an open source toolkit for computer classification of complex social behaviors in experimental animals

SRO Nilsson, NL Goodwin, JJ Choong, S Hwang… - BioRxiv, 2020‏ - biorxiv.org
Aberrant social behavior is a core feature of many neuropsychiatric disorders, yet the study
of complex social behavior in freely moving rodents is relatively infrequently incorporated …

An amygdala-to-hypothalamus circuit for social reward

RK Hu, Y Zuo, T Ly, J Wang, P Meera, YE Wu… - Nature …, 2021‏ - nature.com
Social interactions and relationships are often rewarding, but the neural mechanisms
through which social interaction drives positive experience remain poorly understood. In this …

Sexually dimorphic oxytocin circuits drive intragroup social conflict and aggression in wild house mice

Y Sofer, N Zilkha, E Gimpel, S Wagner… - Nature …, 2024‏ - nature.com
In nature, both males and females engage in competitive aggressive interactions to resolve
social conflicts, yet the behavioral principles guiding such interactions and their underlying …

Fighting females: neural and behavioral consequences of social defeat stress in female mice

EL Newman, HE Covington III, J Suh, MB Bicakci… - Biological …, 2019‏ - Elsevier
Background Despite the twofold higher prevalence of major depressive and posttraumatic
stress disorders in women compared with men, most clinical and preclinical studies have …

Animal models of (or for) aggression reward, addiction, and relapse: behavior and circuits

SA Golden, M **, Y Shaham - Journal of neuroscience, 2019‏ - jneurosci.org
Inappropriate and pathological aggression plays a leading role in the suffering and death of
millions of people, and further places an untenable strain on the caregivers and families of …

The what, how, and why of naturalistic behavior

A Kennedy - Current opinion in neurobiology, 2022‏ - Elsevier
In the past few years, advances in machine learning have fueled an explosive growth of
descriptive and generative models of animal behavior. These new approaches offer higher …

The protective effect of social reward on opioid and psychostimulant reward and relapse: behavior, pharmacology, and brain regions

M Venniro, RAM Marino, JJ Chow, D Caprioli… - Journal of …, 2022‏ - jneurosci.org
Until recently, most modern neuroscience research on addiction using animal models did
not incorporate manipulations of social factors. Social factors play a critical role in human …