Genomic and molecular characterization of esophageal squamous cell carcinoma

DC Lin, JJ Hao, Y Nagata, L Xu, L Shang, X Meng… - Nature …, 2014 - nature.com
Esophageal squamous cell carcinoma (ESCC) is prevalent worldwide and particularly
common in certain regions of Asia. Here we report the whole-exome or targeted deep …

miR‐145, miR‐133a and miR‐133b: Tumor‐suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma

M Kano, N Seki, N Kikkawa, L Fujimura… - … journal of cancer, 2010 - Wiley Online Library
Abstract MicroRNAs (miRNAs), noncoding RNAs 21–25 nucleotides in length, regulate gene
expression primarily at the posttranscriptional level. Growing evidence suggests that …

Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma

X Li, Z Wu, Q Mei, M Guo, X Fu, W Han - British journal of cancer, 2013 - nature.com
Background: HOX transcript antisense RNA (HOTAIR), which is expressed from the
homebox C gene (HOXC) locus, is capable of reprogramming chromatin organisation and …

Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with esophageal squamous cell carcinoma (ESCC) progression and pathogenesis

C Yu, K Chen, H Zheng, X Guo, W Jia, MZ Li… - …, 2009 - academic.oup.com
Abstract Astrocyte elevated gene-1 (AEG-1), upregulated in various types of human cancers,
has been reported to be associated with the carcinogenesis of human cancer. However, the …

The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma

L Hong, Y Han, H Zhang, M Li, T Gong, L Sun… - Annals of …, 2010 - journals.lww.com
Objective: We aimed first to investigate the expression pattern of miRNAs in esophageal
squamous cell cancer and then compared it with those of adjacent benign esophageal …

Epigenetics in esophageal cancers

TD Ahrens, M Werner, S Lassmann - Cell and tissue research, 2014 - Springer
Esophageal cancers are a challenging upper gastrointestinal tract tumor entity for
interdisciplinary oncology. For the two main histotypes, namely esophageal squamous cell …

Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers

MK Kashyap, A Marimuthu, CJH Kishore… - Cancer biology & …, 2009 - Taylor & Francis
Esophageal squamous cell carcinoma (ESCC) is a common cancer worldwide that has a
poor survival rate among patients mainly because of lack of early markers to identify this …

Targeted Knockdown of IQGAP1 Inhibits the Progression of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo

XX Wang, K Wang, XZ Li, LQ Zhai, CX Qu, Y Zhao… - PLoS …, 2014 - journals.plos.org
IQGAP1 is a scaffolding protein that can regulate several distinct signaling pathways. The
accumulating evidence has demonstrated that IQGAP1 plays an important role in …

TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma

PK Hsu, HY Chen, YC Yeh, CC Yen, YC Wu… - Journal of …, 2014 - Springer
Background The molecular and genetic changes underlying esophageal squamous cell
carcinoma (ESCC) tumor formation and rapid progression are poorly understood. Using …

Surgical treatments for esophageal cancers

WH Allum, L Bonavina, SD Cassivi, MA Cuesta… - 2014 - Wiley Online Library
The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes
commentaries on the role of the nurse in preparation of esophageal resection (ER); the …