The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
TJ Littlejohns, J Holliday, LM Gibson, S Garratt… - Nature …, 2020 - nature.com
UK Biobank is a population-based cohort of half a million participants aged 40–69 years
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …
Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis
LM Gibson, L Paul, FM Chappell, M Macleod… - bmj, 2018 - bmj.com
Objectives To determine prevalence and types of potentially serious incidental findings on
magnetic resonance imaging (MRI) in apparently asymptomatic adults, describe factors …
magnetic resonance imaging (MRI) in apparently asymptomatic adults, describe factors …
The Project Baseline Health Study: a step towards a broader mission to map human health
Abstract The Project Baseline Health Study (PBHS) was launched to map human health
through a comprehensive understanding of both the health of an individual and how it …
through a comprehensive understanding of both the health of an individual and how it …
Biobanking and risk assessment: a comprehensive typology of risks for an adaptive risk governance
Biobanks act as the custodians for the access to and responsible use of human biological
samples and related data that have been generously donated by individuals to serve the …
samples and related data that have been generously donated by individuals to serve the …
[HTML][HTML] Genomic health data generation in the UK: a 360 view
E Ormondroyd, P Border, J Hayward… - European Journal of …, 2022 - nature.com
In the UK, genomic health data is being generated in three major contexts: the healthcare
system (based on clinical indication), in large scale research programmes, and for …
system (based on clinical indication), in large scale research programmes, and for …
Return of research results to study participants: uncharted and untested
CA Wong, AF Hernandez, RM Califf - Jama, 2018 - jamanetwork.com
Research data may be of great utility to study participants and their clinicians in
understanding and managing the health of patients who participate in research, depending …
understanding and managing the health of patients who participate in research, depending …
The Yorkshire Kidney Screening Trial (YKST): protocol for a feasibility study of adding non-contrast abdominal CT scanning to screen for kidney cancer and other …
JA Usher-Smith, A Godoy, SW Burge, S Burbidge… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Kidney cancer (renal cell cancer (RCC)) is the seventh most common cancer in
the UK. As RCC is largely curable if detected at an early stage and most patients have no …
the UK. As RCC is largely curable if detected at an early stage and most patients have no …
[HTML][HTML] Abdominal noncontrast computed tomography scanning to screen for kidney cancer and other abdominal pathology within community-based computed …
GD Stewart, A Godoy, F Farquhar, J Kitt, J Cartledge… - European Urology, 2024 - Elsevier
Abstract Background and objective The Yorkshire Kidney Screening Trial (YKST) assessed
the feasibility of adding abdominal noncontrast computed tomography (NCCT) to lung …
the feasibility of adding abdominal noncontrast computed tomography (NCCT) to lung …
An equity and justice-informed ethical framework to guide incidental findings in brain imaging research
SMM Bhaskar - Clinics and Practice, 2023 - mdpi.com
The handling of incidental findings (IFs) in brain imaging studies has been a source of
contention among scientists and bioethicists. A conceptual framework informed by diversity …
contention among scientists and bioethicists. A conceptual framework informed by diversity …
Incidental findings on brain imaging and blood tests: results from the first phase of Insight 46, a prospective observational substudy of the 1946 British birth cohort
SE Keuss, TD Parker, CA Lane, C Hoskote, S Shah… - BMJ open, 2019 - bmjopen.bmj.com
Objective To summarise the incidental findings detected on brain imaging and blood tests
during the first wave of data collection for the Insight 46 study. Design Prospective …
during the first wave of data collection for the Insight 46 study. Design Prospective …