Microbial production of advanced biofuels

J Keasling, H Garcia Martin, TS Lee… - Nature Reviews …, 2021 - nature.com
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

“Metabolic burden” explained: stress symptoms and its related responses induced by (over)expression of (heterologous) proteins in Escherichia coli

S Snoeck, C Guidi, M De Mey - Microbial Cell Factories, 2024 - Springer
Background Engineering bacterial strains to redirect the metabolism towards the production
of a specific product has enabled the development of industrial biotechnology. However …

Production strategies and applications of microbial single cell oils

K Ochsenreither, C Glück, T Stressler… - Frontiers in …, 2016 - frontiersin.org
Polyunsaturated fatty acids (PUFAs) of the ω-3 and ω-6 class (eg, α-linolenic acid, linoleic
acid) are essential for maintaining biofunctions in mammalians like humans. Due to the fact …

Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

A Currin, N Swainston, PJ Day, DB Kell - Chemical Society Reviews, 2015 - pubs.rsc.org
The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

Transformation of biomass into commodity chemicals using enzymes or cells

AJJ Straathof - Chemical reviews, 2014 - ACS Publications
Biomass can be classified broadly as all the matter on the earth's surface of recent biological
origin. 1 Biomass includes plant materials such as trees, grasses, agricultural crops, algal …

Fatty acid synthesis in Escherichia coli and its applications towards the production of fatty acid based biofuels

HJ Janßen, A Steinbüchel - Biotechnology for biofuels, 2014 - Springer
The idea of renewable and regenerative resources has inspired research for more than a
hundred years. Ideally, the only spent energy will replenish itself, like plant material …

Tolerance engineering in bacteria for the production of advanced biofuels and chemicals

A Mukhopadhyay - Trends in microbiology, 2015 - cell.com
During microbial production of solvent-like compounds, such as advanced biofuels and bulk
chemicals, accumulation of the final product can negatively impact the cultivation of the host …

Microbial lipids for foods

SM Ghazani, AG Marangoni - Trends in Food Science & Technology, 2022 - Elsevier
Background Population growth, climate change, and food shortage have led to increased
demand for alternate sources of lipids to meet our food and energy needs. Oleaginous …

The damaging effects of short chain fatty acids on Escherichia coli membranes

LA Royce, P Liu, MJ Stebbins, BC Hanson… - Applied microbiology …, 2013 - Springer
Carboxylic acids are an attractive biorenewable chemical. However, like many other
fermentatively produced compounds, they are inhibitory to the biocatalyst. An understanding …