Low anterior resection syndrome: can it be prevented?

A Annicchiarico, J Martellucci, S Solari… - International journal of …, 2021 - Springer
Surgery remains the cardinal treatment in colorectal cancers but changes in bowel habits
after rectal cancer surgery are common and disabling conditions that affect patients' quality …

Impact of temporary ileostomy on long‐term quality of life and bowel function: a systematic review and meta‐analysis

C Keane, P Sharma, L Yuan, I Bissett… - ANZ journal of …, 2020 - Wiley Online Library
Background Defunctioning ileostomy is widely used to protect a low colorectal anastomosis.
However, the use of an ileostomy may have an impact on long‐term bowel function and …

Low anterior resection syndrome and quality of life after sphincter-sparing rectal cancer surgery: a long-term longitudinal follow-up

EHA Pieniowski, GJ Palmer, T Juul… - Diseases of the Colon …, 2019 - journals.lww.com
BACKGROUND: Despite low anterior resection syndrome being a well-known consequence
of sphincter-preserving rectal cancer surgery, the long-term effect on bowel function and …

Low anterior resection syndrome: a treatment algorithm

J Martellucci - Diseases of the Colon & Rectum, 2016 - journals.lww.com
For almost 100 years abdominoperineal excision has been the standard treatment of choice
for rectal cancer. However, as Miles said,“The operation is a severe one. I do not think that it …

Long-term functional follow-up after anterior rectal resection for cancer

A Sturiale, J Martellucci, L Zurli, C Vaccaro… - International journal of …, 2017 - Springer
Purpose This is a retrospective analysis including all of the patients that have undergone
anterior resection for rectal cancer from January 1998 to December 2005 in two tertiary …

Impact of long-course neoadjuvant radiation on postoperative low anterior resection syndrome and quality of life in rectal cancer: post hoc analysis of a randomized …

W Sun, R Dou, J Chen, S Lai, C Zhang, L Ruan… - Annals of surgical …, 2019 - Springer
Background Neoadjuvant radiation is recommended for locally advanced rectal cancer, with
proven benefit in local control but not in disease-free survival. However, the impact of long …

The longitudinal course of low-anterior resection syndrome: an individual patient meta-analysis

C Varghese, CI Wells, G O'Grady, P Christensen… - Annals of …, 2022 - journals.lww.com
Objective: We aimed to better understand the longitudinal course of low anterior resection
syndrome (LARS) to guide patient expectations and identify those at risk of persisting …

Factors associated with low anterior resection syndrome after surgical treatment of rectal cancer

LM Jimenez‐Gomez, E Espin‐Basany… - Colorectal …, 2018 - Wiley Online Library
Aim The aim was to assess factors independently associated with low anterior resection
syndrome (LARS) following resection for rectal cancer. Method This was a cross‐sectional …

Quality of life and anterior resection syndrome after surgery for mid to low rectal cancer: a cross-sectional study

L Trenti, A Galvez, S Biondo, A Solis… - European Journal of …, 2018 - Elsevier
Background The aim of this study was to analyze the quality of life (QoL), low anterior
resection syndrome (LARS) and fecal incontinence after surgery for mid to low rectal cancer …

Functional outcomes from a randomized trial of early closure of temporary ileostomy after rectal excision for cancer

C Keane, J Park, S Öberg, A Wedin… - Journal of British …, 2019 - academic.oup.com
Background Low anterior resection syndrome (LARS) has a significant impact on
postoperative quality of life. Although early closure of an ileostomy is safe in selected …