India is one of the epicentres of the global diabetes mellitus pandemic. Rapid
socioeconomic development and demographic changes, along with increased susceptibility …

The “fetal” or “early” origins of adult disease hypothesis was originally put forward by David
Barker and colleagues and stated that environmental factors, particularly nutrition, act in …

Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

The incidence of the metabolic syndrome, a cluster of abnormalities focusing on insulin
resistance and associated with high risk for cardiovascular disease and diabetes, is …

An adverse prenatal environment may induce long-term metabolic consequences, in
particular obesity and insulin resistance. Although the mechanisms are unclear, this …

BACKGROUND & AIMS: Obesity induced, non-alcoholic fatty liver disease (NAFLD), is now
the major cause in affluent countries, of the spectrum of steatosis-to-cirrhosis. Obesity and …

The hormone leptin is secreted from white adipocytes, and serum levels of leptin correlate
with adipose tissue mass. Leptin was first described to act on the satiety center in the …

Maternal nutrition plays a decisive role in developmental programming of many non-
communicable diseases (NCDs). A variety of nutritional insults during gestation can cause …

The discovery of a link between in utero experience and later metabolic and cardiovascular
disease is one of the most important advances in epidemiology research of recent years …

Nutrient restriction during pregnancy and lactation impairs growth and development. Recent
studies demonstrate long‐term programming of function of specific organ systems resulting …