Secondary ion mass spectrometry (SIMS) is a technique for chemical analysis and imaging
of solid materials, with applications in many areas of science and technology. It involves …

Biological systems are composed of heterogeneous populations of cells that
intercommunicate to form a functional living tissue. Biological function varies greatly across …

Lipids are an important class of biomolecules with many roles within cells and tissue. As
targets for study, they present several challenges. They are difficult to label, as many labels …

High spatial resolution mass spectrometry imaging has been identified as a key technology
needed to improve understanding of the chemical components that influence antibiotic …

Basal cell carcinoma (BCC) is the most common skin malignancy. In fact, it is as common as
the sum of all other skin malignancies combined and the incidence is rising. In this focused …

Cocaine dependence displays a broad impairment in cognitive performance including
attention, learning, and memory. To obtain a better understanding of the action of cocaine in …

Abstract Changes in the membrane composition of sub-populations of cells can influence
different properties with importance to tumour growth, metastasis and treatment efficacy. In …

The mechanism of synaptic plasticity and its link to memory formation are of interest, yet
relatively obscure, especially the initial chemical change in the cell membrane following …

Mass spectrometry imaging (MSI) is a label‐free imaging technique capable of
simultaneously imaging hundreds of molecular species and is widely applied to imaging …

Time‐of‐flight secondary ion mass spectrometry (ToF‐SIMS) using a primary ion beam of
(CO2) 6k+ was used to analyse chemical changes in the bacterial envelope of a fabF knock …