Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

The past decade has witnessed an explosion in the use of super-resolution fluorescence
microscopy methods in biology and other fields. Single-molecule localization microscopy …

Super-resolution fluorescence microscopy is a powerful tool for biological research, but
obtaining multiplexed images for a large number of distinct target species remains …

Super-resolution fluorescence imaging by photoactivation or photoswitching of single
fluorophores and position determination (single-molecule localization microscopy, SMLM) …

Super-resolution imaging has rapidly emerged as an optical microscopy technique, offering
advantages of high optical resolution over the past two decades; achieving improved …

We developed a method to use any GFP-tagged construct in single-molecule super-
resolution microscopy. By targeting GFP with small, high-affinity antibodies coupled to …

Super-resolution microscopy (SRM) methods have allowed scientists to exceed the
diffraction limit of light, enabling the discovery and investigation of cellular structures at the …

Single-molecule biophysics has transformed our understanding of biology, but also of the
physics of life. More exotic than simple soft matter, biomatter lives far from thermal …

Recent advances in fluorescence super-resolution microscopy have allowed subcellular
features and synthetic nanostructures down to 10–20 nm in size to be imaged. However, the …

Bax is a key regulator of apoptosis that, under cell stress, accumulates at mitochondria,
where it oligomerizes to mediate the permeabilization of the mitochondrial outer membrane …