Research progress on dendritic cell vaccines in cancer immunotherapy

J Yu, H Sun, W Cao, Y Song, Z Jiang - Experimental hematology & …, 2022 - Springer
Dendritic cell (DC) vaccines induce specific immune responses that can selectively
eliminate target cells. In recent years, many studies have been conducted to explore DC …

Recent advances in experimental dendritic cell vaccines for cancer

IY Filin, KV Kitaeva, CS Rutland, AA Rizvanov… - Frontiers in …, 2021 - frontiersin.org
The development of immunotherapeutic methods for the treatment of oncological diseases
have made it possible to improve the effectiveness of standard therapies. There was no …

[HTML][HTML] Immunotherapy in soft tissue and bone sarcoma: unraveling the barriers to effectiveness

M Panagi, P Pilavaki, A Constantinidou… - Theranostics, 2022 - ncbi.nlm.nih.gov
Sarcomas are uncommon malignancies of mesenchymal origin that can arise throughout the
human lifespan, at any part of the body. Surgery remains the optimal treatment modality …

Exosome-based immunotherapy as an innovative therapeutic approach in melanoma

S Babaei, M Fadaee, H Abbasi-Kenarsari… - Cell Communication and …, 2024 - Springer
The malignant form of melanoma is one of the deadliest human cancers that accounts for
almost all of the skin tumor-related fatalities in its later stages. Achieving an exhaustive …

Dendritic cell vaccine therapy for colorectal cancer

AL Wooster, LH Girgis, H Brazeale, TS Anderson… - Pharmacological …, 2021 - Elsevier
Colorectal cancer (CRC) remains a leading cause of cancer-related deaths in the United
States despite an array of available treatment options. Current standard-of-care …

Tumor microenvironmental influences on dendritic cell and T cell function: A focus on clinically relevant immunologic and metabolic checkpoints

KM Hargadon - Clinical and Translational Medicine, 2020 - Wiley Online Library
Cancer immunotherapy is fast becoming one of the most promising means of treating
malignant disease. Cancer vaccines, adoptive cell transfer therapies, and immune …

Dysfunction of dendritic cells in tumor microenvironment and immunotherapy

J Chen, Y Duan, J Che, J Zhu - Cancer Communications, 2024 - Wiley Online Library
Dendritic cells (DCs) comprise diverse cell populations that play critical roles in antigen
presentation and triggering immune responses in the body. However, several factors impair …

First step results from a phase II study of a dendritic cell vaccine in glioblastoma patients (CombiG-vax)

L Ridolfi, L Gurrieri, N Riva, J Bulgarelli… - Frontiers in …, 2024 - frontiersin.org
Background Glioblastoma (GBM) is a poor prognosis grade 4 glioma. After surgical
resection, the standard therapy consists of concurrent radiotherapy (RT) and temozolomide …

Dendritic cell vaccine as a potential strategy to end the COVID-19 pandemic. Why should it be Ex Vivo?

J Jonny, TA Putranto, EC Sitepu… - Expert Review of Vaccines, 2022 - Taylor & Francis
Introduction Develo** a safe and efficacious vaccine that can induce broad and long-term
immunity for SARS-CoV-2 infection is the most critical research to date. As the most potent …

Dendritic cell subsets in melanoma: Pathophysiology, clinical prognosis and therapeutic exploitation

E Sosa Cuevas, P Saas, C Aspord - Cancers, 2023 - mdpi.com
Simple Summary The clinical success of immunotherapies using immune checkpoint
blockers deployed in melanoma strongly supports that the immune system can efficiently …