Immunomodulation by radiotherapy in tumour control and normal tissue toxicity
UM Cytlak, DP Dyer, J Honeychurch… - Nature Reviews …, 2022 - nature.com
Radiotherapy (RT) is a highly effective anticancer treatment that is delivered to more than
half of all patients with cancer. In addition to the well-documented direct cytotoxic effects, RT …
half of all patients with cancer. In addition to the well-documented direct cytotoxic effects, RT …
Mucositis: pathobiology and management
Oral mucositis is a common complication of cancer treatment that may negatively impact the
patient's cancer treatment outcome. Despite its frequency and consequences, the lack of …
patient's cancer treatment outcome. Despite its frequency and consequences, the lack of …
Radioprotection and radiomitigation: from the bench to clinical practice
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
Emerging evidence on the pathobiology of mucositis
Background Considerable progress has been made in our understanding of the biological
basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of …
basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of …
Mechanisms of inflammatory responses to radiation and normal tissues toxicity: clinical implications
Purpose: Cancer treatment is one of the most challenging diseases in the present era.
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …
Systematic review of anti-inflammatory agents for the management of oral mucositis in cancer patients and clinical practice guidelines
Purpose The aim of this systematic review was to update the clinical practice guidelines for
the use of anti-inflammatory agents in the prevention and/or treatment of oral mucositis …
the use of anti-inflammatory agents in the prevention and/or treatment of oral mucositis …
Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression
Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting
from defects in insulin secretion and/or action. One of the most important complications of …
from defects in insulin secretion and/or action. One of the most important complications of …
Anti‐inflammatory cytokines: important immunoregulatory factors contributing to chemotherapy‐induced gastrointestinal mucositis
“Mucositis” is the clinical term used to describe ulceration and damage of the mucous
membranes of the entire gastrointestinal tract (GIT) following cytotoxic cancer chemotherapy …
membranes of the entire gastrointestinal tract (GIT) following cytotoxic cancer chemotherapy …
Melatonin protects rats from radiotherapy-induced small intestine toxicity
Radiotherapy-induced gut toxicity is among the most prevalent dose-limiting toxicities
following radiotherapy. Prevention of radiation enteropathy requires protection of the small …
following radiotherapy. Prevention of radiation enteropathy requires protection of the small …
Implication of nano-antioxidant therapy for treatment of hepatocellular carcinoma using PLGA nanoparticles of rutin
P Pandey, M Rahman, PC Bhatt, S Beg, B Paul… - …, 2018 - Taylor & Francis
Aim: The present work describes the development of poly (lactic co-glycolic acid)(PLGA)
nanoparticles (NPs) of rutin (RT) for the treatment of hepatocellular carcinoma in rats …
nanoparticles (NPs) of rutin (RT) for the treatment of hepatocellular carcinoma in rats …