[HTML][HTML] The influence of drugs used for sedation during mechanical ventilation on respiratory pattern during unassisted breathing and assisted mechanical ventilation …

D Quickfall, MC Sklar, G Tomlinson… - …, 2024 - thelancet.com
Background Sedation management has a major impact on outcomes in mechanically
ventilated patients, but sedation strategies do not generally consider the differential effects of …

Tracheostomy: update on why, when and how

G Lais, L Piquilloud - Current opinion in critical care, 2025 - journals.lww.com
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Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients

M van den Berg, Z Shi, WJ Claassen… - Science translational …, 2024 - science.org
Patients receiving mechanical ventilation in the intensive care unit (ICU) frequently develop
contractile weakness of the diaphragm. Consequently, they may experience difficulty …

Effect of aggressive vs conservative screening and confirmatory test on time to extubation among patients at low or intermediate risk: a randomized clinical trial

G Hernández Martínez, P Rodriguez, J Soto… - Intensive Care …, 2024 - Springer
Purpose This study aimed to determine the best strategy to achieve fast and safe extubation.
Methods This multicenter trial randomized patients with primary respiratory failure and low-to …

Diaphragm dysfunction predicts weaning outcome after bilateral lung transplant

A Boscolo, N Sella, T Pettenuzzo, E Pistollato… - …, 2023 - ingentaconnect.com
Background: Diaphragm dysfunction and its effects on outcomes of ventilator weaning have
been evaluated in mixed critical care populations using diaphragm thickening fraction (the …

Electrical Impedance Tomography as a monitoring tool during weaning from mechanical ventilation: an observational study during the spontaneous breathing trial

JJ Wisse, TG Goos, AH Jonkman, P Somhorst… - Respiratory …, 2024 - Springer
Background Prolonged weaning from mechanical ventilation is associated with poor clinical
outcome. Therefore, choosing the right moment for weaning and extubation is essential …

Utilization of spontaneous breathing trial, objective cough test, and diaphragmatic ultrasound results to predict extubation success: COBRE-US trial

F Varón-Vega, LF Giraldo-Cadavid, AM Uribe… - Critical Care, 2023 - Springer
Background The results of clinical and weaning readiness tests and the spontaneous
breathing trial (SBT) are used to predict the success of the weaning process and extubation …

Spontaneous breathing trials should be adapted for each patient according to the critical illness. A new individualised approach: the GLOBAL WEAN study

M Capdevila, Y Aarab, C Monet, A De Jong… - Intensive Care …, 2024 - Springer
Purpose Spontaneous breathing trials (SBT) evaluate the patient's capacity to maintain
inspiratory effort after extubation. SBT practices are heterogeneous and not individualised …

In-hospital mortality, comorbidities, and costs of one million mechanically ventilated patients in Germany: a nationwide observational study before, during, and after the …

C Karagiannidis, F Krause, C Bentlage… - The Lancet Regional …, 2024 - thelancet.com
Background Even more than hospital care in general, intensive care and mechanical
ventilation capacities and its utilization in terms of rates, indications, ventilation types and …

Impact of sleep disturbances on outcomes in intensive care units

L Marchasson, C Rault, S Le Pape, F Arrivé, R Coudroy… - Critical Care, 2024 - Springer
Background Sleep deprivation is common in intensive care units (ICUs) and may alter
respiratory performance. Few studies have assessed the role of sleep disturbances on …