Patients requiring mechanical ventilation (MV) beyond 21 days, usually referred to as
prolonged MV, represent a unique group with significant medical needs and a generally …

Background Sedation management has a major impact on outcomes in mechanically
ventilated patients, but sedation strategies do not generally consider the differential effects of …

Patients receiving mechanical ventilation in the intensive care unit (ICU) frequently develop
contractile weakness of the diaphragm. Consequently, they may experience difficulty …

Purpose This study aimed to determine the best strategy to achieve fast and safe extubation.
Methods This multicenter trial randomized patients with primary respiratory failure and low-to …

Background Even more than hospital care in general, intensive care and mechanical
ventilation capacities and its utilization in terms of rates, indications, ventilation types and …

Given the aging population with increasing morbidity but also importantly scientific and
technological advances that prolong the ability to support survival in intensive care, the …

Background Prolonged weaning from mechanical ventilation is associated with poor clinical
outcome. Therefore, choosing the right moment for weaning and extubation is essential …

Background Weaning from invasive mechanical ventilation (MV) is a complex and
challenging process that involves multiple pathophysiological mechanisms. A combined …

Background: Diaphragm dysfunction and its effects on outcomes of ventilator weaning have
been evaluated in mixed critical care populations using diaphragm thickening fraction (the …

Purpose To provide consensus recommendations regarding hemodynamic data reporting in
studies investigating fluid responsiveness and fluid challenge (FC) use in the intensive care …