The nexus between RNA-binding proteins and their effectors

S He, E Valkov, S Cheloufi, J Murn - Nature Reviews Genetics, 2023 - nature.com
RNA-binding proteins (RBPs) regulate essentially every event in the lifetime of an RNA
molecule, from its production to its destruction. Whereas much has been learned about RNA …

Integrins in development: moving on, responding to, and sticking to the extracellular matrix

C Bökel, NH Brown - Developmental cell, 2002 - cell.com
Integrins are cell surface receptors of the extracellular matrix present in all animals. Genetic
analysis in worms, flies, and vertebrates has revealed integrin involvement in key …

Connecting muscles to tendons: tendons and musculoskeletal development in flies and vertebrates

R Schweitzer, E Zelzer, T Volk - Development, 2010 - journals.biologists.com
The formation of the musculoskeletal system represents an intricate process of tissue
assembly involving heterotypic inductive interactions between tendons, muscles and …

Target RNA motif and target mRNAs of the Quaking STAR protein

A Galarneau, S Richard - Nature structural & molecular biology, 2005 - nature.com
Quaking viable (Qk v) mice have developmental defects that result in their characteristic
tremor. The quaking (Qk) locus expresses alternatively spliced RNA-binding proteins …

Sam68, the KH domain-containing superSTAR

KE Lukong, S Richard - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2003 - Elsevier
Sam68 is one of the most studied members of the STAR family of RNA-binding proteins
since its identification over a decade ago. Since its ascension into prominence, enormous …

Emerging functions of the Quaking RNA‐binding proteins and link to human diseases

L Darbelli, S Richard - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
RNA‐binding proteins (RBPs) are essential players in RNA metabolism including key
cellular processes from pre‐mRNA splicing to mRNA translation. The K homology‐type …

Nuclear retention of MBP mRNAs in the quaking viable mice

D Larocque, J Pilotte, T Chen, F Cloutier, B Massie… - Neuron, 2002 - cell.com
Quaking viable (qk v) mice fail to properly compact myelin in their central nervous systems.
Although the defect in the qk v mice involves a mutation affecting the expression of the …

New implications for the QUAKING RNA binding protein in human disease

CA Chénard, S Richard - Journal of neuroscience research, 2008 - Wiley Online Library
The use of spontaneously occurring mouse models has proved to be a valuable tool
throughout the years to delineate the signals required for nervous system development. This …

Analysis of Gal4 Expression Patterns in Adult Drosophila Females

LN Weaver, T Ma… - G3: Genes, Genomes …, 2020 - academic.oup.com
Precise genetic manipulation of specific cell types or tissues to pinpoint gene function
requirement is a critical step in studies aimed at unraveling the intricacies of organismal …

Muscle building: mechanisms of myotube guidance and attachment site selection

F Schnorrer, BJ Dickson - Developmental cell, 2004 - cell.com
The complex muscle patterns of higher organisms arise as migrating myoblasts are guided
toward and connect with specific attachment sites. We review here the current …