[HTML][HTML] New insights into the latest advancement in α-amylase inhibitors of plant origin with anti-diabetic effects

H Kashtoh, KH Baek - Plants, 2023 - mdpi.com
The rising predominance of type 2 diabetes, combined with the poor medical effects seen
with commercially available anti-diabetic medications, has motivated the development of …

[HTML][HTML] LC/MS-MS Analysis of Phenolic Compounds in Hyoscyamus albus L. Extract: In Vitro Antidiabetic Activity, In Silico Molecular Docking, and In Vivo …

S Lekmine, O Benslama, K Kadi, AI Martín-García… - Pharmaceuticals, 2023 - mdpi.com
This study aimed to investigate the chemical composition and antidiabetic properties of
cultivated Hyoscyamus albus L. The ethanol extract was analyzed using LC-MS/MS, and 18 …

[HTML][HTML] Solid-state fermentation for phenolic compounds recovery from mexican oregano (Lippia graveolens Kunth) residual leaves applying a lactic acid bacteria …

I Bautista-Hernández, R Gómez-García, CN Aguilar… - Agriculture, 2024 - mdpi.com
The Mexican oregano by-products are a source of bioactive molecules (polyphenols) that
could be extracted using solid-state fermentation (SSF). This study fermented the by …

Phenolic compounds and antioxidant activity of Lippia graveolens Kunth residual leaves fermented by two filamentous fungal strains in solid-state process

I Bautista-Hernández, CN Aguilar… - Food and Bioproducts …, 2022 - Elsevier
The residual leaves from essential oil extraction from Mexican oregano (Lippia graveolens)
have a potential as a source of bioactive molecules (ex flavonoids) that could be extracted …

Machine learning combined with molecular simulations to screen α-amylase inhibitors as compounds that regulate blood sugar

B Liu, B Zhang, L Li, K Wang, Y Zhang, J Zhou… - Process …, 2024 - Elsevier
Diabetes, a metabolic disease characterized by hyperglycemia, seriously endangers the
health and the lives of people. α-Amylase inhibitors have become effective substances to …

α-Amylase and mycobacterium-TB H37Rv antagonistic efficacy of novel pyrazole-coumarin hybrids: an in vitro and in silico investigation

DC Kanjariya, HN Naik, MJ Sherashiya… - Journal of …, 2024 - Taylor & Francis
The present investigation of minutiae to acquire structural information of the novel pyrazole-
coumarin hybrids (PC1-PC10) synthesized using ultrasound methods and characterized …

Synthesis, Corrosion Inhibition, In Silico ADME, DFT, and Antibacterial Activity of Pyridine‐Based Schiff Base and Its Cu (II) Complex

NK Chaudhary, B Guragain… - Applied …, 2024 - Wiley Online Library
Herein, we report the synthesis of an (E)‐N‐(pyridine‐3‐ylmethylene) pyridine‐2‐amine
Schiff base (ENppa) and its Cu (II) complex (Cu‐ENppa) using 2‐aminopyridine (2APy) and …

Lignans in Patrinia with various biological activities and extensive application value: A review

X Meng, J Qu, X Yang, S Zhang, Y Zhang… - Journal of Food …, 2024 - isnff-jfb.com
Lignans in Patrinia have attracted the attention of researchers due to their diverse structure
and remarkable activity. We searched the PubMed database for articles published from …

Novel Design of an α-Amylase with an N-Terminal CBM20 in Aspergillus niger Improves Binding and Processing of a Broad Range of Starches

A Sidar, GP Voshol, E Vijgenboom, PJ Punt - Molecules, 2023 - mdpi.com
In the starch processing industry including the food and pharmaceutical industries, α-
amylase is an important enzyme that hydrolyses the α-1, 4 glycosidic bonds in starch …

GC–MS analysis, molecular docking, and pharmacokinetic studies on Dalbergia sissoo barks extracts for compounds with anti-diabetic potential

D Vijh, P Gupta - Scientific Reports, 2024 - nature.com
Diabetes is a metabolic condition defined by abnormal blood sugar levels. Targeting starch-
hydrolyzing enzymes and Dipeptidyl Peptidase 4 (DPP-4) expressed on the surface of …