[HTML][HTML] Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update

A Sharma, KL Sharma, A Gupta, A Yadav… - World journal of …, 2017 - ncbi.nlm.nih.gov
Gallbladder cancer is a malignancy of biliary tract which is infrequent in developed countries
but common in some specific geographical regions of develo** countries. Late diagnosis …

Gallbladder cancer: current insights in genetic alterations and their possible therapeutic implications

H Kuipers, TJJ de Bitter, MT de Boer, RS van der Post… - Cancers, 2021 - mdpi.com
Simple Summary Knowledge of genetic alterations in gallbladder cancer (GBC) continues to
increase. This systematic review provides an overview of frequently occurring genetic …

[HTML][HTML] Gall bladder carcinoma: Aggressive malignancy with protean loco-regional and distant spread

AND Dwivedi, S Jain, R Dixit - World Journal of Clinical Cases …, 2015 - ncbi.nlm.nih.gov
The most common malignancy of biliary tract is gallbladder cancer (GBC) which is the third
most common cancer in gastrointestinal tract. It is a lethal disease for most patients in spite …

Molecular pathogenesis of gallbladder cancer: An update

SK Mishra, N Kumari, N Krishnani - Mutation Research/Fundamental and …, 2019 - Elsevier
Gallbladder carcinoma (GBC) is the most aggressive gastrointestinal malignancy throughout
the world, with wide geographical variance. It is the subtype of biliary tract malignancy that …

Genetic landscape of gallbladder cancer: global overview

R Mehrotra, S Tulsyan, S Hussain, B Mittal… - … Research/Reviews in …, 2018 - Elsevier
Gallbladder cancer (GBC) is a rare malignancy of biliary tract cancer (BTC), characterized by
late presentation and poor prognosis. It exhibits wide geographical as well as ethnical …

Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy

C Bizama, P García, JA Espinoza, H Weber… - Cancer Treatment …, 2015 - Elsevier
Gallbladder cancer is the most common and aggressive malignancy of the biliary tract. The
complete surgical resection is the only potentially curative approach in early stage; however …

Regional differences in gallbladder cancer pathogenesis: Insights from a multi‐institutional comparison of tumor mutations

RR Narayan, JM Creasy, DA Goldman, M Gönen… - Cancer, 2019 - Wiley Online Library
Background Although rare in the United States, gallbladder cancer (GBCA) is a common
cause of cancer death in some parts of the world. To investigate regional differences in …

Gallbladder cancer: Progress in the Indian subcontinent

A Kumar, Y Sarangi, A Gupta… - World Journal of Clinical …, 2024 - pmc.ncbi.nlm.nih.gov
Gallbladder cancer (GBC) is one of the commonest biliary malignancies seen in India,
Argentina, and Japan. The disease has dismal outcome as it is detected quite late due to …

TNF-alpha promotes lymphangiogenesis and lymphatic metastasis of gallbladder cancer through the ERK1/2/AP-1/VEGF-D pathway

HJ Hong, L Jiang, YF Lin, CL He, GW Zhu, Q Du… - BMC cancer, 2016 - Springer
Background Tumor necrosis factor-alpha (TNF-α), a key player in cancer-related
inflammation, was recently demonstrated to be involved in the lymphatic metastasis of …

Targeted therapy in biliary tract cancers

A Merla, KG Liu, L Rajdev - Current treatment options in oncology, 2015 - Springer
Opinion statement A paradigm shift towards molecular-based, personalized cancer
therapeutics has occurred in recent years and a number of targeted drugs have emerged …